Associations of dietary intake with cardiovascular disease, blood pressure, and lipid profile in the korean population: A systematic review and meta-analysis

Jeongseon Kim, Tung Hoang, So Young Bu, Ji Myung Kim, Jeong Hwa Choi, Eunju Park, Seung Min Lee, Eunmi Park, Ji Yeon Min, In Seok Lee, So Young Youn

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)


Objective: Previous studies have separately reported the contributions of dietary factors to the risk of cardiovascular disease (CVD) and its markers, including blood pressure (BP) and lipid profile. This study systematically reviewed the current evidence on this issue in the Korean population. Methods: Sixty-two studies from PubMed and Embase were included in this meta-analysis. We performed a random-effects model to analyze pooled odds ratios (ORs) and hazard ratios (HRs) and their 95% confidence intervals (CIs) for the consumption of 14 food items, three macro-and eight micro-nutrients, two dietary patterns, and three dietary indices. Results: An analysis of pooled effect sizes from at least four individual study populations showed significant associations between coffee consumption and CVD (OR/HR, 0.71; 95% CI, 0.52–0.97) and elevated/high triglycerides (TG) (OR, 0.84; 95% CI, 0.78–0.90), sugarsweetened beverage intake and elevated BP (OR/HR, 1.20; 95% CI, 1.09–1.33), and milk and dairy intake and elevated/high TG and low high-density lipoprotein cholesterol (HDL-C) (OR/HR, 0.82; 95% CI, 0.76–0.89 for both). Carbohydrate consumption and the lowcarbohydrate-diet score were consistently related to an approximately 25% risk reduction for elevated TG and low HDL-C. A lower risk of elevated total cholesterol, but not low-density lipoprotein, was additionally observed for those with a higher low-carbohydrate-diet score. A healthy dietary pattern was only associated with a reduced risk of elevated TG in the Korea National Cancer Screenee Cohort (OR, 0.81; 95% CI, 0.67–0.98). Conclusion: This study showed that milk and dairy and coffee had protective effects for CVD and its risk factors, such as BP and lipid profile, while sugar-sweetened beverages exerted harmful effects.

Original languageEnglish
Pages (from-to)205-229
Number of pages25
JournalJournal of Lipid and Atherosclerosis
Issue number1
Publication statusPublished - 2020 Jan

Bibliographical note

Publisher Copyright:
© 2020 The Korean Society of Lipid and Atherosclerosis.

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine


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