Association of serum ferritin levels with non-alcoholic fatty liver disease in postmenopausal women

H. B. Kim, H. S. Lee, Y. J. Lee

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7 Citations (Scopus)


Objective: This study aimed to investigate the association between serum ferritin levels and the presence of non-alcoholic fatty liver disease (NAFLD) in postmenopausal women. Methods: Two hundred and forty-one postmenopausal women who participated in a heath examination program were enrolled in the present study. Serum ferritin tertiles were categorized as follows: T1, ≤46.4 ng/ml; T2, 46.5–76.1 ng/ml; and T3, ≥76.2 ng/ml. The odds ratios (ORs) and 95% confidence intervals (CIs) for NAFLD were calculated after adjusting for confounding variables across serum ferritin tertiles using multiple logistic regression analysis. Results: The overall prevalence of NAFLD was 41.4% and was significantly increased in accordance with the serum ferritin tertiles as follows: 30.0% for T1, 40.7% for T2, and 54.3% for T3, respectively. As compared with the lowest tertile, the OR (95% CI) for NAFLD in the highest tertile was 2.69 (1.16–5.28) after adjusting for age, body mass index, regular exercise, mean arterial pressure, fasting plasma glucose, triglyceride, high-density lipoprotein cholesterol, alanine aminotransferase, and leukocyte count. Conclusion: The serum ferritin level was positively and independently associated with NAFLD in postmenopausal women and could be a useful additional measure in assessing the risk of NAFLD in postmenopausal women.

Original languageEnglish
Pages (from-to)509-514
Number of pages6
Issue number5
Publication statusPublished - 2018 Sept 3

Bibliographical note

Publisher Copyright:
© 2018, © 2018 International Menopause Society.

All Science Journal Classification (ASJC) codes

  • Obstetrics and Gynaecology


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