TY - JOUR
T1 - Association between serum triglyceride to high-density lipoprotein cholesterol ratio and sarcopenia in elderly Korean males
T2 - The Korean National Health and Nutrition Examination Survey
AU - Chung, Tae Ha
AU - Kwon, Yu Jin
AU - Shim, Jae Yong
AU - Lee, Yong Jae
N1 - Publisher Copyright:
© 2016 Elsevier B.V.
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Background We investigated the association between the triglycerides to high-density lipoprotein cholesterol (TG/HDL) ratio and sarcopenia in elderly Korean males. Methods We examined the relationship between the TG/HDL ratio and sarcopenia in 879 elderly males ≥ 60 years who participated in the 2010–2011 KNHANES. Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by the weight (%), which is > 1 SD below the mean for young adults. The odds ratios (ORs) for sarcopenia were calculated using multiple logistic regression across the TG/HDL ratio quartiles (Q1: ≤ 1.4, Q2: 1.5–2.4, Q3: 2.5–3.8 and Q4: ≥ 3.9) after adjusting for confounding variables. Results The prevalence of sarcopenia significantly increased in accordance with TG/HDL ratio quartiles. Compared with the lowest quartile of the TG/HDL ratio, the corresponding OR (95% CI) of the highest quartile of the TG/HDL ratio for sarcopenia was 2.10 (1.12–3.91) after adjusting for age, body mass index (BMI), cigarette smoking, alcohol intake and physical activity. Conclusion TG/HDL ratio was positively related with a higher risk of sarcopenia in elderly Korean males.
AB - Background We investigated the association between the triglycerides to high-density lipoprotein cholesterol (TG/HDL) ratio and sarcopenia in elderly Korean males. Methods We examined the relationship between the TG/HDL ratio and sarcopenia in 879 elderly males ≥ 60 years who participated in the 2010–2011 KNHANES. Sarcopenia was defined as an appendicular skeletal muscle mass (ASM) divided by the weight (%), which is > 1 SD below the mean for young adults. The odds ratios (ORs) for sarcopenia were calculated using multiple logistic regression across the TG/HDL ratio quartiles (Q1: ≤ 1.4, Q2: 1.5–2.4, Q3: 2.5–3.8 and Q4: ≥ 3.9) after adjusting for confounding variables. Results The prevalence of sarcopenia significantly increased in accordance with TG/HDL ratio quartiles. Compared with the lowest quartile of the TG/HDL ratio, the corresponding OR (95% CI) of the highest quartile of the TG/HDL ratio for sarcopenia was 2.10 (1.12–3.91) after adjusting for age, body mass index (BMI), cigarette smoking, alcohol intake and physical activity. Conclusion TG/HDL ratio was positively related with a higher risk of sarcopenia in elderly Korean males.
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U2 - 10.1016/j.cca.2016.10.032
DO - 10.1016/j.cca.2016.10.032
M3 - Article
C2 - 27983997
AN - SCOPUS:84993986324
SN - 0009-8981
VL - 463
SP - 165
EP - 168
JO - Clinica Chimica Acta
JF - Clinica Chimica Acta
ER -