Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease

Jaehyun Bae; Byung Wan Lee

doi:10.3390/biom13101506

Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease

Jaehyun Bae, Byung Wan Lee

Department of Internal Medicine

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

Abstract

Metabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the disposal of fatty acids in the liver and its metabolic benefits have been reported. In this review, we examined previous studies on the association between ketogenesis and MAFLD and reviewed the candidate mechanisms that can explain this association.

Original language	English
Article number	1506
Journal	Biomolecules
Volume	13
Issue number	10
DOIs	https://doi.org/10.3390/biom13101506
Publication status	Published - 2023 Oct

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology

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10.3390/biom13101506

Cite this

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title = "Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease",

abstract = "Metabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the disposal of fatty acids in the liver and its metabolic benefits have been reported. In this review, we examined previous studies on the association between ketogenesis and MAFLD and reviewed the candidate mechanisms that can explain this association.",

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author = "Jaehyun Bae and Lee, {Byung Wan}",

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AU - Bae, Jaehyun

AU - Lee, Byung Wan

PY - 2023/10

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N2 - Metabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the disposal of fatty acids in the liver and its metabolic benefits have been reported. In this review, we examined previous studies on the association between ketogenesis and MAFLD and reviewed the candidate mechanisms that can explain this association.

AB - Metabolic (dysfunction) associated fatty liver disease (MAFLD) is generally developed with excessive accumulation of lipids in the liver. Ketogenesis is an efficient pathway for the disposal of fatty acids in the liver and its metabolic benefits have been reported. In this review, we examined previous studies on the association between ketogenesis and MAFLD and reviewed the candidate mechanisms that can explain this association.

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KW - ketone

KW - metabolic-associated fatty liver disease

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Association between Impaired Ketogenesis and Metabolic-Associated Fatty Liver Disease

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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