Aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT) detection techniques

Xing Jiu Huang, Yang Kyu Choi, Hyung Soon Im, Oktay Yarimaga, Euisik Yoon, Hak Sung Kim

Research output: Contribution to journalReview articlepeer-review

228 Citations (Scopus)


The levels of aspartate aminotransferase (AST/GOT) and alanine aminotransferase (ALT/GPT) in serum can help people diagnose body tissues especially the heart and the liver are injured or not. This article provides a comprehensive review of research activities that concentrate on AST/GOT and ALT/GPT detection techniques due to their clinical importance. The detection techniques include colorimetric, spectrophotometric, chemiluminescence, chromatography, fluorescence and UV absorbance, radiochemical, and electrochemical techniques. We devote the most attention on experimental principle. In some methods a few representative devices and important conclusions are presented.

Original languageEnglish
Pages (from-to)756-782
Number of pages27
Issue number7
Publication statusPublished - 2006

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Electrical and Electronic Engineering


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