Antimicrobial and biodegradable PLGA medical sutures with natural grapefruit seed extracts

Hye Sun Lee, So Hyun Park, Jin Hyung Lee, Bong Yong Jeong, Sang Kook Ahn, Young Muk Choi, Doo Jin Choi, Jeong Ho Chang

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


This work demonstrates the development of novel antimicrobial and biodegradable suture coated by natural extract from grape fruit. The natural extract is loaded to PLGA suture and their optimum conditions are determined as a function of soaking time, loaded volume, and releasing time. Furthermore, the evaluation of antibacterial effect was achieved by Staphylococcus aureus and Escherchia DH5α with the used amounts and released time. The cell growth was calculated for several days through 2 months. The physicochemical properties of antimicrobial and biodegradable PLGA suture are demonstrated.

Original languageEnglish
Pages (from-to)40-43
Number of pages4
JournalMaterials Letters
Publication statusPublished - 2013

Bibliographical note

Funding Information:
This research was supported by a Grant no. 08K1501-01110 from the Center for Nano-structured Materials Technology under the 21st Century Frontier R&D Programs of the Ministry of Education, Science and Technology, Korea.

All Science Journal Classification (ASJC) codes

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering


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