Antimicrobial and biodegradable PLGA medical sutures with natural grapefruit seed extracts

Hye Sun Lee; So Hyun Park; Jin Hyung Lee; Bong Yong Jeong; Sang Kook Ahn; Young Muk Choi; Doo Jin Choi; Jeong Ho Chang

doi:10.1016/j.matlet.2012.12.090

Antimicrobial and biodegradable PLGA medical sutures with natural grapefruit seed extracts

Hye Sun Lee, So Hyun Park, Jin Hyung Lee, Bong Yong Jeong, Sang Kook Ahn, Young Muk Choi, Doo Jin Choi, Jeong Ho Chang

Department of Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

This work demonstrates the development of novel antimicrobial and biodegradable suture coated by natural extract from grape fruit. The natural extract is loaded to PLGA suture and their optimum conditions are determined as a function of soaking time, loaded volume, and releasing time. Furthermore, the evaluation of antibacterial effect was achieved by Staphylococcus aureus and Escherchia DH5α with the used amounts and released time. The cell growth was calculated for several days through 2 months. The physicochemical properties of antimicrobial and biodegradable PLGA suture are demonstrated.

Original language	English
Pages (from-to)	40-43
Number of pages	4
Journal	Materials Letters
Volume	95
DOIs	https://doi.org/10.1016/j.matlet.2012.12.090
Publication status	Published - 2013

Bibliographical note

Funding Information:
This research was supported by a Grant no. 08K1501-01110 from the Center for Nano-structured Materials Technology under the 21st Century Frontier R&D Programs of the Ministry of Education, Science and Technology, Korea.

All Science Journal Classification (ASJC) codes

Materials Science(all)
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

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10.1016/j.matlet.2012.12.090

Cite this

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title = "Antimicrobial and biodegradable PLGA medical sutures with natural grapefruit seed extracts",

abstract = "This work demonstrates the development of novel antimicrobial and biodegradable suture coated by natural extract from grape fruit. The natural extract is loaded to PLGA suture and their optimum conditions are determined as a function of soaking time, loaded volume, and releasing time. Furthermore, the evaluation of antibacterial effect was achieved by Staphylococcus aureus and Escherchia DH5α with the used amounts and released time. The cell growth was calculated for several days through 2 months. The physicochemical properties of antimicrobial and biodegradable PLGA suture are demonstrated.",

author = "Lee, {Hye Sun} and Park, {So Hyun} and Lee, {Jin Hyung} and Jeong, {Bong Yong} and Ahn, {Sang Kook} and Choi, {Young Muk} and Choi, {Doo Jin} and Chang, {Jeong Ho}",

note = "Funding Information: This research was supported by a Grant no. 08K1501-01110 from the Center for Nano-structured Materials Technology under the 21st Century Frontier R&D Programs of the Ministry of Education, Science and Technology, Korea.",

year = "2013",

doi = "10.1016/j.matlet.2012.12.090",

language = "English",

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T1 - Antimicrobial and biodegradable PLGA medical sutures with natural grapefruit seed extracts

AU - Lee, Hye Sun

AU - Park, So Hyun

AU - Lee, Jin Hyung

AU - Jeong, Bong Yong

AU - Ahn, Sang Kook

AU - Choi, Young Muk

AU - Choi, Doo Jin

AU - Chang, Jeong Ho

N1 - Funding Information: This research was supported by a Grant no. 08K1501-01110 from the Center for Nano-structured Materials Technology under the 21st Century Frontier R&D Programs of the Ministry of Education, Science and Technology, Korea.

PY - 2013

Y1 - 2013

N2 - This work demonstrates the development of novel antimicrobial and biodegradable suture coated by natural extract from grape fruit. The natural extract is loaded to PLGA suture and their optimum conditions are determined as a function of soaking time, loaded volume, and releasing time. Furthermore, the evaluation of antibacterial effect was achieved by Staphylococcus aureus and Escherchia DH5α with the used amounts and released time. The cell growth was calculated for several days through 2 months. The physicochemical properties of antimicrobial and biodegradable PLGA suture are demonstrated.

AB - This work demonstrates the development of novel antimicrobial and biodegradable suture coated by natural extract from grape fruit. The natural extract is loaded to PLGA suture and their optimum conditions are determined as a function of soaking time, loaded volume, and releasing time. Furthermore, the evaluation of antibacterial effect was achieved by Staphylococcus aureus and Escherchia DH5α with the used amounts and released time. The cell growth was calculated for several days through 2 months. The physicochemical properties of antimicrobial and biodegradable PLGA suture are demonstrated.

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DO - 10.1016/j.matlet.2012.12.090

M3 - Article

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SN - 0167-577X

VL - 95

SP - 40

EP - 43

JO - Materials Letters

JF - Materials Letters

ER -

Antimicrobial and biodegradable PLGA medical sutures with natural grapefruit seed extracts

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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