Amphiphilic graft copolymers consisting of poly(vinyl chloride) (PVC) main chains and poly(4-vinyl pyridine) (P4VP) side chains were synthesized via atom transfer radical polymerization (ATRP) using direct initiation of chlorine atoms. The successful synthesis of PVC-g-P4VP graft copolymers was confirmed by Fourier transform infrared spectroscopy (FTIR) and proton nuclear magnetic resonance (1H-NMR). Transmission electron microscope (TEM) and small angle X-ray scattering (SAXS) analysis showed that PVC-g-P4VP exhibited microphase-separated, ordered structure with 37.6 nm of domain spacing, which was not observed in neat PVC. For antibacterial applications, the tertiary nitrogen atoms of PVC-g-P4VP was quaternized using 1-bromohexane, as confirmed by FTIR measurements. Bacteria including Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), Bacillus cereus (B. cereus), and Pseudomonas aeruginosa (P. aeruginosa) were completely killed in 24 h on the quaternized PVC-g-P4VP (46% grafting) surface, indicating its excellent antibacterial behavior while it showed to be cytotoxic to mammalian cell.
|Number of pages||10|
|Journal||Chinese Journal of Polymer Science (English Edition)|
|Publication status||Published - 2015 Feb|
Bibliographical noteFunding Information:
This work was financially supported by a National Research Foundation (NRF) grant funded by the Korean government (MEST) through the Core Research Program (2012R1A2A2A02011268), Agriculture Research Center program of Ministry for Food, Agriculture, Forestry, and Fisheries (IPET 112051-3), the Korea CCS R&D Center and the Energy Efficiency & Resources of the Korea Institute of Energy Technology Evaluation and Planning (KETEP) grant funded by the Ministry of Knowledge Economy (20122010100040).
© 2015, Chinese Chemical Society, Institute of Chemistry, Chinese Academy of Sciences and Springer-Verlag Berlin Heidelberg.
All Science Journal Classification (ASJC) codes
- Chemical Engineering(all)
- Polymers and Plastics
- Organic Chemistry