An Ultrasensitive, Visco-Poroelastic Artificial Mechanotransducer Skin Inspired by Piezo2 Protein in Mammalian Merkel Cells

Ming Liang Jin; Sangsik Park; Younghoon Lee; Ji Hye Lee; Junho Chung; Joo Sung Kim; Jong Seon Kim; So Young Kim; Eunsong Jee; Dae Woo Kim; Jae Woo Chung; Seung Geol Lee; Dukhyun Choi; Hee Tae Jung; Do Hwan Kim

doi:10.1002/adma.201605973

An Ultrasensitive, Visco-Poroelastic Artificial Mechanotransducer Skin Inspired by Piezo2 Protein in Mammalian Merkel Cells

Ming Liang Jin, Sangsik Park, Younghoon Lee, Ji Hye Lee, Junho Chung, Joo Sung Kim, Jong Seon Kim, So Young Kim, Eunsong Jee, Dae Woo Kim, Jae Woo Chung, Seung Geol Lee, Dukhyun Choi, Hee Tae Jung, Do Hwan Kim

Department of Chemical and Biomolecular Engineering

Research output: Contribution to journal › Article › peer-review

136 Citations (Scopus)

Abstract

Researchers describe a mechanically activated visco-poroelastic nanochannel on the basis of artificial ionic fluids and a viscoelastic biocompatible polymer network to closely emulate the Piezo2 nanochannel in epidermal mammalian Merkel cells. They implemented these in a piezocapacitive artificial ionic mechanotransducer (IMT) that involved the sequential pressing, chain deformation, and ion migration process. They also enhanced an effective output stress by introducing the pillar-type microstructure on the surface of visco-poroelastic film, thereby resulting in inducing an efficient squeezing-out of ionic liquids at even low stimuli. The artificial IMT exhibited ultrahigh sensitivity and operational stability over a wide range of mechanical stimuli, including conditions conducive to real-time ubiquitous health care, daily activities, and even weight measurement.

Original language	English
Article number	1605973
Journal	Advanced Materials
Volume	29
Issue number	13
DOIs	https://doi.org/10.1002/adma.201605973
Publication status	Published - 2017 Apr 4

Bibliographical note

Funding Information:
M.L.J. and S.P. contributed equally to this work. This work was financially supported by the Center for Advanced Soft-Electronics under the Global Frontier Project (CASE-2014M3A6A5060932 and CASE-2014M3A6A5060937) and the Basic Science Research Program (2014R1A1A1005933 and 2015R1A2A1A05001844) of the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning.

All Science Journal Classification (ASJC) codes

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201605973

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Jin, M. L., Park, S., Lee, Y., Lee, J. H., Chung, J., Kim, J. S., Kim, J. S., Kim, S. Y., Jee, E., Kim, D. W., Chung, J. W., Lee, S. G., Choi, D., Jung, H. T., & Kim, D. H. (2017). An Ultrasensitive, Visco-Poroelastic Artificial Mechanotransducer Skin Inspired by Piezo2 Protein in Mammalian Merkel Cells. Advanced Materials, 29(13), Article 1605973. https://doi.org/10.1002/adma.201605973

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abstract = "Researchers describe a mechanically activated visco-poroelastic nanochannel on the basis of artificial ionic fluids and a viscoelastic biocompatible polymer network to closely emulate the Piezo2 nanochannel in epidermal mammalian Merkel cells. They implemented these in a piezocapacitive artificial ionic mechanotransducer (IMT) that involved the sequential pressing, chain deformation, and ion migration process. They also enhanced an effective output stress by introducing the pillar-type microstructure on the surface of visco-poroelastic film, thereby resulting in inducing an efficient squeezing-out of ionic liquids at even low stimuli. The artificial IMT exhibited ultrahigh sensitivity and operational stability over a wide range of mechanical stimuli, including conditions conducive to real-time ubiquitous health care, daily activities, and even weight measurement.",

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An Ultrasensitive, Visco-Poroelastic Artificial Mechanotransducer Skin Inspired by Piezo2 Protein in Mammalian Merkel Cells

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

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