An implantable wireless optogenetic stimulation system for peripheral nerve control

Kang Il Song; Sunghee E. Park; Myoung Soo Kim; Chulmin Joo; Yong Jun Kim; Jun Kyo F. Suh; Dosik Hwang; Inchan Youn

doi:10.1109/EMBC.2015.7318541

An implantable wireless optogenetic stimulation system for peripheral nerve control

Kang Il Song, Sunghee E. Park, Myoung Soo Kim, Chulmin Joo, Yong Jun Kim, Jun Kyo F. Suh, Dosik Hwang, Inchan Youn

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

7 Citations (Scopus)

Abstract

An implantable wireless optogenetic stimulation system with an LED-based optical stimulation cuff electrode was developed for peripheral nerve control. The proposed system consisted of a battery-powered optical cuff electrode, optical stimulation controller, and wireless communication system. The optical cuff electrode had a polydimethylsiloxane (PDMS) structure was designed to illuminate the entire sciatic nerve. The wireless communication system was designed to comply with medical implant communication service (MICS) regulations. To evaluate the proposed system, optogenetic stimulation was performed in optogenetic transgenic mice (Thy1::ChR2). The optical cuff electrode was implanted on the sciatic nerve, and movement was elicited during optical stimulation. The experimental results show that ankle movement can be generated wirelessly using optical stimulation pulse parameters.

Original language	English
Title of host publication	2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	1033-1036
Number of pages	4
ISBN (Electronic)	9781424492718
DOIs	https://doi.org/10.1109/EMBC.2015.7318541
Publication status	Published - 2015 Nov 4
Event	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 - Milan, Italy Duration: 2015 Aug 25 → 2015 Aug 29

Publication series

Name	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Volume	2015-November
ISSN (Print)	1557-170X

Other

Other	37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015
Country/Territory	Italy
City	Milan
Period	15/8/25 → 15/8/29

Bibliographical note

Publisher Copyright:
© 2015 IEEE.

All Science Journal Classification (ASJC) codes

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Access to Document

10.1109/EMBC.2015.7318541

Cite this

Song, K. I., Park, S. E., Kim, M. S., Joo, C., Kim, Y. J., Suh, J. K. F., Hwang, D., & Youn, I. (2015). An implantable wireless optogenetic stimulation system for peripheral nerve control. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015 (pp. 1033-1036). [7318541] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2015-November). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/EMBC.2015.7318541

Song, Kang Il ; Park, Sunghee E. ; Kim, Myoung Soo et al. / An implantable wireless optogenetic stimulation system for peripheral nerve control. 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. pp. 1033-1036 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

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title = "An implantable wireless optogenetic stimulation system for peripheral nerve control",

abstract = "An implantable wireless optogenetic stimulation system with an LED-based optical stimulation cuff electrode was developed for peripheral nerve control. The proposed system consisted of a battery-powered optical cuff electrode, optical stimulation controller, and wireless communication system. The optical cuff electrode had a polydimethylsiloxane (PDMS) structure was designed to illuminate the entire sciatic nerve. The wireless communication system was designed to comply with medical implant communication service (MICS) regulations. To evaluate the proposed system, optogenetic stimulation was performed in optogenetic transgenic mice (Thy1::ChR2). The optical cuff electrode was implanted on the sciatic nerve, and movement was elicited during optical stimulation. The experimental results show that ankle movement can be generated wirelessly using optical stimulation pulse parameters.",

author = "Song, {Kang Il} and Park, {Sunghee E.} and Kim, {Myoung Soo} and Chulmin Joo and Kim, {Yong Jun} and Suh, {Jun Kyo F.} and Dosik Hwang and Inchan Youn",

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doi = "10.1109/EMBC.2015.7318541",

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Song, KI, Park, SE, Kim, MS, Joo, C , Kim, YJ, Suh, JKF, Hwang, D & Youn, I 2015, An implantable wireless optogenetic stimulation system for peripheral nerve control. in 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015., 7318541, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, vol. 2015-November, Institute of Electrical and Electronics Engineers Inc., pp. 1033-1036, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 15/8/25. https://doi.org/10.1109/EMBC.2015.7318541

An implantable wireless optogenetic stimulation system for peripheral nerve control. / Song, Kang Il; Park, Sunghee E.; Kim, Myoung Soo et al.
2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc., 2015. p. 1033-1036 7318541 (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS; Vol. 2015-November).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Song KI, Park SE, Kim MS, Joo C , Kim YJ, Suh JKF et al. An implantable wireless optogenetic stimulation system for peripheral nerve control. In 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015. Institute of Electrical and Electronics Engineers Inc. 2015. p. 1033-1036. 7318541. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). doi: 10.1109/EMBC.2015.7318541

An implantable wireless optogenetic stimulation system for peripheral nerve control

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