An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia

Mun Yong Lee; Yun Sik Choi; Jeong Sun Choi; Do Sik Min; Myung Hoon Chun; Ok Nyu Kim; Sang Bok Lee; Seong Yun Kim

doi:10.1016/S0006-8993(01)03295-4

An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia

Mun Yong Lee, Yun Sik Choi, Jeong Sun Choi, Do Sik Min, Myung Hoon Chun, Ok Nyu Kim, Sang Bok Lee, Seong Yun Kim

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.

Original language	English
Pages (from-to)	237-241
Number of pages	5
Journal	Brain Research
Volume	924
Issue number	2
DOIs	https://doi.org/10.1016/S0006-8993(01)03295-4
Publication status	Published - 2002 Jan 11

All Science Journal Classification (ASJC) codes

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/S0006-8993(01)03295-4

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title = "An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia",

abstract = "The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.",

author = "Lee, {Mun Yong} and Choi, {Yun Sik} and Choi, {Jeong Sun} and Min, {Do Sik} and Chun, {Myung Hoon} and Kim, {Ok Nyu} and Lee, {Sang Bok} and Kim, {Seong Yun}",

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AU - Lee, Mun Yong

AU - Choi, Yun Sik

AU - Choi, Jeong Sun

AU - Min, Do Sik

AU - Chun, Myung Hoon

AU - Kim, Ok Nyu

AU - Lee, Sang Bok

AU - Kim, Seong Yun

PY - 2002/1/11

Y1 - 2002/1/11

N2 - The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.

AB - The cellular localization and spatiotemporal expression pattern of APG-2 protein, a member of the heat shock protein 110 family, were investigated in the rat hippocampus after transient forebrain ischemia. The spatiotemporal patterns of immunoreactivity of both APG-2 and glial fibrillary acidic protein were very similar, indicating that reactive astrocytes express APG-2, which was confirmed by double immunofluorescence histochemistry. Colocalization of APG-2 and a neuronal marker NeuN in the neurons of the CA2 and CA3 subfields was also confirmed.

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An immunohistochemical study of APG-2 protein in the rat hippocampus after transient forebrain ischemia

Abstract

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