An ESIPT-based fluorescent turn-on probe with isothiocyanate for detecting hydrogen sulfide in environmental and biological systems

Jae Kyong Kim, So Yeon Bong, Rackhyun Park, Junsoo Park, Doo Ok Jang

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

A probe with an isothiocyanate group was synthesized and evaluated for its H2S sensing ability. Upon addition of H2S, the probe exhibited ratiometric properties during absorption with a red-shift. The probe exhibited fluorescent off–on responses towards H2S via the ESIPT process, due to the conversion of isocyanate into amine. UV–vis, fluorescence, and 1H NMR spectroscopic analyses were performed to investigate the sensing mechanism. The probe has a large Stokes shift, short response time, and low detection limit. It can be used to estimate H2S levels within the range of 0–36 nM. The practical applicability of the probe was demonstrated using water samples and living cells.

Original languageEnglish
Article number121333
JournalSpectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volume278
DOIs
Publication statusPublished - 2022 Oct 5

Bibliographical note

Publisher Copyright:
© 2022 Elsevier B.V.

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Atomic and Molecular Physics, and Optics
  • Instrumentation
  • Spectroscopy

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