TY - GEN
T1 - An electrodynamic preconcentrator-integrated thermoelectric biosensor chip for continuous MONITORING
AU - Choi, Yong Hwan
AU - Kang, Dong Hyun
AU - Yoon, Seung Il
AU - Kim, Min Gu
AU - Sim, Jaesam
AU - Kim, Jongbaeg
AU - Kim, Yong Jun
PY - 2011
Y1 - 2011
N2 - An integrated thermoelectric biosensor chip is being proposed for continuous monitoring of biochemical process. It is composed of a preconcentrator and a thermoelectric biosensor. In the preconcentrator, the concentration of the biochemical sample is electrodynamically condensed, which results in enhancement of the sensitivity of the integrated sensor. Then, in the sensor, the preconcentrated target molecules interact with injected capture molecules and generate reaction heat. The reaction heat is detected based on thermoelectric effect with an integrated split-flow micro channel which provides self-compensation of thermal noise. In the fabricated biochip, 95.8% of the sample was concentrated to be 2.88-fold and detected with the sensitivity of 54.7V/molarity in biotin-streptavidin application.
AB - An integrated thermoelectric biosensor chip is being proposed for continuous monitoring of biochemical process. It is composed of a preconcentrator and a thermoelectric biosensor. In the preconcentrator, the concentration of the biochemical sample is electrodynamically condensed, which results in enhancement of the sensitivity of the integrated sensor. Then, in the sensor, the preconcentrated target molecules interact with injected capture molecules and generate reaction heat. The reaction heat is detected based on thermoelectric effect with an integrated split-flow micro channel which provides self-compensation of thermal noise. In the fabricated biochip, 95.8% of the sample was concentrated to be 2.88-fold and detected with the sensitivity of 54.7V/molarity in biotin-streptavidin application.
UR - http://www.scopus.com/inward/record.url?scp=79953794925&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953794925&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2011.5734555
DO - 10.1109/MEMSYS.2011.5734555
M3 - Conference contribution
AN - SCOPUS:79953794925
SN - 9781424496327
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 837
EP - 840
BT - 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011
T2 - 24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011
Y2 - 23 January 2011 through 27 January 2011
ER -