An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67

Hee Jae Shin; M. A.Mojid Mondol; Tae Kyung Yu; Hyi Seung Lee; Yeon Ju Lee; Hye Jin Jung; Jong Hyeon Kim; Ho Jeong Kwon

doi:10.1016/j.phytol.2010.07.005

An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67

Hee Jae Shin, M. A.Mojid Mondol, Tae Kyung Yu, Hyi Seung Lee, Yeon Ju Lee, Hye Jin Jung, Jong Hyeon Kim, Ho Jeong Kwon

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

Cyclo-(l-Pro-l-Met) was isolated from the fermentation broth of a marine-derived actinomycete Nocardiopsis sp. 03N67 by chromatographic analysis and showed anti-angiogenesis activity against human umbilical vein endothelial cells (HUVECs). The structure and absolute stereochemistry of this compound were determined based on extensive spectroscopic data analysis, and Marfey's method, respectively.

Original language	English
Pages (from-to)	194-197
Number of pages	4
Journal	Phytochemistry Letters
Volume	3
Issue number	4
DOIs	https://doi.org/10.1016/j.phytol.2010.07.005
Publication status	Published - 2010 Dec 17

Bibliographical note

Funding Information:
The authors express gratitude to Y.H. Kim, Korea Basic Science Institute, Daejeon, Korea, for providing mass data. This research was supported in part by the Ministry of Land, Transport and Maritime Affairs, Korea , Korea Ocean Research and Development Institute (Grants PE98472 to D.H.K. and PE98494 to H.S.P.) and the Translational Research Center for Protein Function Control ( NRF 2009-0083522 to H.J.K.).

All Science Journal Classification (ASJC) codes

Biotechnology
Biochemistry
Agronomy and Crop Science
Plant Science

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.phytol.2010.07.005

Cite this

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title = "An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67",

abstract = "Cyclo-(l-Pro-l-Met) was isolated from the fermentation broth of a marine-derived actinomycete Nocardiopsis sp. 03N67 by chromatographic analysis and showed anti-angiogenesis activity against human umbilical vein endothelial cells (HUVECs). The structure and absolute stereochemistry of this compound were determined based on extensive spectroscopic data analysis, and Marfey's method, respectively.",

author = "Shin, {Hee Jae} and Mondol, {M. A.Mojid} and Yu, {Tae Kyung} and Lee, {Hyi Seung} and Lee, {Yeon Ju} and Jung, {Hye Jin} and Kim, {Jong Hyeon} and Kwon, {Ho Jeong}",

note = "Funding Information: The authors express gratitude to Y.H. Kim, Korea Basic Science Institute, Daejeon, Korea, for providing mass data. This research was supported in part by the Ministry of Land, Transport and Maritime Affairs, Korea , Korea Ocean Research and Development Institute (Grants PE98472 to D.H.K. and PE98494 to H.S.P.) and the Translational Research Center for Protein Function Control ( NRF 2009-0083522 to H.J.K.).",

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doi = "10.1016/j.phytol.2010.07.005",

language = "English",

volume = "3",

pages = "194--197",

journal = "Phytochemistry Letters",

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AU - Shin, Hee Jae

AU - Mondol, M. A.Mojid

AU - Yu, Tae Kyung

AU - Lee, Hyi Seung

AU - Lee, Yeon Ju

AU - Jung, Hye Jin

AU - Kim, Jong Hyeon

AU - Kwon, Ho Jeong

N1 - Funding Information: The authors express gratitude to Y.H. Kim, Korea Basic Science Institute, Daejeon, Korea, for providing mass data. This research was supported in part by the Ministry of Land, Transport and Maritime Affairs, Korea , Korea Ocean Research and Development Institute (Grants PE98472 to D.H.K. and PE98494 to H.S.P.) and the Translational Research Center for Protein Function Control ( NRF 2009-0083522 to H.J.K.).

PY - 2010/12/17

Y1 - 2010/12/17

N2 - Cyclo-(l-Pro-l-Met) was isolated from the fermentation broth of a marine-derived actinomycete Nocardiopsis sp. 03N67 by chromatographic analysis and showed anti-angiogenesis activity against human umbilical vein endothelial cells (HUVECs). The structure and absolute stereochemistry of this compound were determined based on extensive spectroscopic data analysis, and Marfey's method, respectively.

AB - Cyclo-(l-Pro-l-Met) was isolated from the fermentation broth of a marine-derived actinomycete Nocardiopsis sp. 03N67 by chromatographic analysis and showed anti-angiogenesis activity against human umbilical vein endothelial cells (HUVECs). The structure and absolute stereochemistry of this compound were determined based on extensive spectroscopic data analysis, and Marfey's method, respectively.

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An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67

Abstract

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

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