Acute respiratory distress syndrome after the use of gadolinium contrast media

Jihye Park, Il Hwan Byun, Kyung Hee Park, Jae Hyun Lee, Eun Ji Nam, Jung Won Park

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13 Citations (Scopus)


Acute respiratory distress syndrome (ARDS) is a medical emergency that threatens life. To this day, ARDS is very rarely reported by iodine contrast media, and there is no reported case of ARDS induced by gadolinium contrast media. Here, we present a case with ARDS after the use of gadobutrol (Gadovist) as a magnetic resonance imaging (MRI) contrast medium. A 26 years old female without any medical history, including allergic diseases and without current use of drugs, visited the emergency room for abdominal pain. Her abdominopelvic computed tomography with iodine contrast media showed a right ovarian cyst and possible infective colitis. Eighty-three hours later, she underwent pelvis MRI after injection of 7.5 mL (0.1 mL/kg body weight) of gadobutrol (Gadovist) to evaluate the ovarian cyst. She soon presented respiratory difficulty, edema of the lips, nausea, and vomiting, and we could hear wheezing upon auscultation. She was treated with dexamethasone, epinephrine, and norepinephrine. Her chest X-ray showed bilateral central bat-wing consolidative appearance. Managed with mechanical ventilation, she was extubated 3 days later and discharged without complications.

Original languageEnglish
Pages (from-to)1155-1157
Number of pages3
JournalYonsei medical journal
Issue number4
Publication statusPublished - 2015 Jul 1

Bibliographical note

Publisher Copyright:
© Yonsei University College of Medicine 2015.

All Science Journal Classification (ASJC) codes

  • General Medicine


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