A soft and transparent contact lens for the wireless quantitative monitoring of intraocular pressure

Joohee Kim, Jihun Park, Young Geun Park, Eunkyung Cha, Minjae Ku, Hyeon Seok An, Kyoung Pil Lee, Man Il Huh, Junmo Kim, Taek Soo Kim, Dai Woo Kim, Hong Kyun Kim, Jang Ung Park

Research output: Contribution to journalArticlepeer-review

92 Citations (Scopus)

Abstract

Continuous detection of raised intraocular pressure (IOP) could benefit the monitoring of patients with glaucoma. Current contact lenses with embedded sensors for measuring IOP are rigid, bulky, partially block vision or are insufficiently sensitive. Here, we report the design and testing in volunteers of a soft and transparent contact lens for the quantitative monitoring of IOP in real time using a smartphone. The contact lens incorporates a strain sensor, a wireless antenna, capacitors, resistors, stretchable metal interconnects and an integrated circuit for wireless communication. In rabbits, the lens provided measurements that match those of a commercial tonometer. In ten human participants, the lens proved to be safe, and reliably provided accurate quantitative measurements of IOP without inducing inflammation.

Original languageEnglish
Pages (from-to)772-782
Number of pages11
JournalNature biomedical engineering
Volume5
Issue number7
DOIs
Publication statusPublished - 2021 Jul

Bibliographical note

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Nature Limited.

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Medicine (miscellaneous)
  • Biomedical Engineering
  • Computer Science Applications

Fingerprint

Dive into the research topics of 'A soft and transparent contact lens for the wireless quantitative monitoring of intraocular pressure'. Together they form a unique fingerprint.

Cite this