A preliminary study of clinical abbreviation disambiguation in real time

Y. Wu, J. C. Denny, S. T. Rosenbloom, R. A. Miller, D. A. Giuse, M. Song, Hua Xu

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)


Objective: To save time, healthcare providers frequently use abbreviations while authoring clinical documents. Nevertheless, abbreviations that authors deem unambiguous often confuse other readers, including clinicians, patients, and natural language processing (NLP) systems. Most current clinical NLP systems “post-process” notes long after clinicians enter them into electronic health record systems (EHRs). Such post-processing cannot guarantee 100% accuracy in abbreviation identification and disambiguation, since multiple alternative interpretations exist. Methods: Authors describe a prototype system for real-time Clinical Abbreviation Recognition and Disambiguation (rCARD) – i.e., a system that interacts with authors during note generation to verify correct abbreviation senses. The rCARD system design anticipates future integration with webbased clinical documentation systems to improve quality of healthcare records. When clinicians enter documents, rCARD will automatically recognize each abbreviation. For abbreviations with multiple possible senses, rCARD will show a ranked list of possible meanings with the best predicted sense at the top. The prototype application embodies three word sense disambiguation (WSD) methods to predict the correct senses of abbreviations. We then conducted three experments to evaluate rCARD, including 1) a performance evaluation of different WSD methods; 2) a time evaluation of real-time WSD methods; and 3) a user study of typing clinical sentences with abbreviations using rCARD. Results: Using 4,721 sentences containing 25 commonly observed, highly ambiguous clinical abbreviations, our evaluation showed that the best profile-based method implemented in rCARD achieved a reasonable WSD accuracy of 88.8% (comparable to SVM – 89.5%) and the cost of time for the different WSD methods are also acceptable (ranging from 0.630 to 1.649 milliseconds within the same network). The preliminary user study also showed that the extra time costs by rCARD were about 5% of total document entry time and users did not feel a significant delay when using rCARD for clinical document entry. Conclusion: The study indicates that it is feasible to integrate a real-time, NLP-enabled abbreviation recognition and disambiguation module with clinical documentation systems.

Original languageEnglish
Pages (from-to)364-374
Number of pages11
JournalApplied Clinical Informatics
Issue number2
Publication statusPublished - 2015

Bibliographical note

Publisher Copyright:
© Schattauer 2015.

All Science Journal Classification (ASJC) codes

  • Health Informatics
  • Computer Science Applications
  • Health Information Management


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