TY - GEN
T1 - A patient-specific model of virtual ablation for atrial fibrillation
AU - Kwon, Soon Sung
AU - Yun, Yong Hyun
AU - Hong, Seung Bae
AU - Pak, Hui Nam
AU - Shim, Eun Bo
PY - 2013
Y1 - 2013
N2 - The purpose of this study was to propose a patient-specific model of atrial fibrillation (AF) and apply it to virtual radiofrequency ablation (RFA). We obtained patient-specific geometries of the left atrium (LA) from CT data and constructed three-dimensional (3D) simulation models. A bidomain Courtemanche model was used to simulate the 3D electric waves on the LA surface, and an S1-S2 protocol was applied to induce AF in the model. To identify scar areas in the models, we converted clinically measured voltage data on the LA surface to the scar maps of the simulation model. Then, after initiation of AF, we applied the virtual ablation scheme to the model and investigated whether the AF was terminated by the scheme. The computed results of AF and ablation were similar to those of clinical observation, providing a clinically important simulation method for preclinical virtual trials of AF treatment.
AB - The purpose of this study was to propose a patient-specific model of atrial fibrillation (AF) and apply it to virtual radiofrequency ablation (RFA). We obtained patient-specific geometries of the left atrium (LA) from CT data and constructed three-dimensional (3D) simulation models. A bidomain Courtemanche model was used to simulate the 3D electric waves on the LA surface, and an S1-S2 protocol was applied to induce AF in the model. To identify scar areas in the models, we converted clinically measured voltage data on the LA surface to the scar maps of the simulation model. Then, after initiation of AF, we applied the virtual ablation scheme to the model and investigated whether the AF was terminated by the scheme. The computed results of AF and ablation were similar to those of clinical observation, providing a clinically important simulation method for preclinical virtual trials of AF treatment.
UR - http://www.scopus.com/inward/record.url?scp=84886509568&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84886509568&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2013.6609802
DO - 10.1109/EMBC.2013.6609802
M3 - Conference contribution
C2 - 24109989
AN - SCOPUS:84886509568
SN - 9781457702167
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 1522
EP - 1525
BT - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
T2 - 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Y2 - 3 July 2013 through 7 July 2013
ER -