A novel radiation-resistant strain of Filobasidium sp. isolated from the West Sea of Korea

Harinder Singh, Haram Kim, Hyunpa Song, Minho Joe, Dongho Kim, Yong Sun Bahn, Jong Il Choi, Sangyong Lim

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


A novel radiation-resistant Filobasidium sp. yeast strain was isolated from seawater. Along with this strain, a total of 656 yeast isolates were purified from seawater samples collected from three locations in the West Sea of Korea and assessed for their radiation tolerance. Among these isolates, five were found to survive a 5 kGy radiation dose. The most radiation-resistant strain was classified as Filobasidium sp. based on 18S rDNA sequence analysis and hence was named Filobasidium RRY1 (Radiation-Resistant Yeast 1). RRY1 differed from F. elegans, which is closely related to RRY1, in terms of the optimal growth temperature and radiation resistance, and was resistant to high doses of γ-ionizing radiation (D10: 6-7 kGy). When exposed to a high dose of 3 kGy irradiation, the RRY1 cells remained intact and undistorted, with negligible cell death. When these irradiated cells were allowed to recover, the cells fully repaired their genomic DNA within 3 h of growth recovery. This is the first report in which a radiation-resistant response has been investigated at the physiological, morphological, and molecular levels in a strain of Filobasidium sp.

Original languageEnglish
Pages (from-to)1493-1499
Number of pages7
JournalJournal of microbiology and biotechnology
Issue number11
Publication statusPublished - 2013

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology


Dive into the research topics of 'A novel radiation-resistant strain of Filobasidium sp. isolated from the West Sea of Korea'. Together they form a unique fingerprint.

Cite this