A new simple iterative reconstruction algorithm for SPECT transmission measurement

Do Sik Hwang, Gengsheng L. Zeng

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


This paper proposes a new iterative reconstruction algorithm for transmission tomography and compares this algorithm with several other methods. The new algorithm is simple and resembles the emission ML-EM algorithm in form. Due to its simplicity, it is easy to implement and fast to compute a new update at each iteration. The algorithm also always guarantees non-negative solutions. Evaluations are performed using simulation studies and real phantom data. Comparisons with other algorithms such as convex, gradient, and logMLEM show that the proposed algorithm is as good as others and performs better in some cases.

Original languageEnglish
Pages (from-to)2312-2319
Number of pages8
JournalMedical physics
Issue number7
Publication statusPublished - 2005 Jul

Bibliographical note

Funding Information:
This work was supported by the National Institutes of Biomedical Imaging and Bioengineering, and National Cancer Institute of the National Institutes of Health under grants CA 100181 and EB00121. We thank Dr. Roy Rowley of the Utah Center for Advanced Imaging Research for editing our manuscript.

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Radiology Nuclear Medicine and imaging


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