A new integron carrying VIM-2 metallo-β-lactamase gene cassette in a Serratia marcescens isolate

Jong Hwa Yum; Dongeun Yong; Kyungwon Lee; Hyon Suk Kim; Yunsop Chong

doi:10.1016/S0732-8893(01)00352-2

A new integron carrying VIM-2 metallo-β-lactamase gene cassette in a Serratia marcescens isolate

Jong Hwa Yum, Dongeun Yong, Kyungwon Lee, Hyon Suk Kim, Yunsop Chong

Department of Laboratory Medicine

Research output: Contribution to journal › Article › peer-review

63 Citations (Scopus)

Abstract

Serratia marcescens is an important nosocomial pathogen which is often resistant to multiple antimicrobial agents. An imipenem-resistant S. marcescens isolate from a urine specimen was found to carry a bla_VIM-2 gene cassette on a class 1 integron. This finding indicates that bla_VIM-2 is presently spreading even to Serratia spp. in Korea, which could compromise the usefulness of carbapenem in the treatment of multi-resistant Gram-negative bacilli infections. Clinical laboratory should be able to detect the VIM-2-producing isolates with even low carbapenem MIC.

Original language	English
Pages (from-to)	217-219
Number of pages	3
Journal	Diagnostic Microbiology and Infectious Disease
Volume	42
Issue number	3
DOIs	https://doi.org/10.1016/S0732-8893(01)00352-2
Publication status	Published - 2002

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

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10.1016/S0732-8893(01)00352-2

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abstract = "Serratia marcescens is an important nosocomial pathogen which is often resistant to multiple antimicrobial agents. An imipenem-resistant S. marcescens isolate from a urine specimen was found to carry a blaVIM-2 gene cassette on a class 1 integron. This finding indicates that blaVIM-2 is presently spreading even to Serratia spp. in Korea, which could compromise the usefulness of carbapenem in the treatment of multi-resistant Gram-negative bacilli infections. Clinical laboratory should be able to detect the VIM-2-producing isolates with even low carbapenem MIC.",

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AU - Kim, Hyon Suk

AU - Chong, Yunsop

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AB - Serratia marcescens is an important nosocomial pathogen which is often resistant to multiple antimicrobial agents. An imipenem-resistant S. marcescens isolate from a urine specimen was found to carry a blaVIM-2 gene cassette on a class 1 integron. This finding indicates that blaVIM-2 is presently spreading even to Serratia spp. in Korea, which could compromise the usefulness of carbapenem in the treatment of multi-resistant Gram-negative bacilli infections. Clinical laboratory should be able to detect the VIM-2-producing isolates with even low carbapenem MIC.

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A new integron carrying VIM-2 metallo-β-lactamase gene cassette in a Serratia marcescens isolate

Abstract

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