A genomics approach using expressed sequence tags and microarrays in ripening apple fruit (Malus domestica Borkh.)

Young Sam Seo, Woo Taek Kim

Research output: Contribution to journalReview articlepeer-review

5 Citations (Scopus)


Apple (Malus domestica Borkh.), an important horticultural crop, produces human health-promoting metabolites during fruit ripening. Because that process, which involves complex biochemical and physiological changes, is genetically programmed, molecular and genetic approaches have been taken to understand the associated cellular mechanisms. The release of 151,687 apple expressed sequence tags (ESTs) into a public database has made possible large-scale studies of expression. Analysis of apple ESTs allows for the identification and characterization of genes with potential roles in fruit development, particularly those related to aroma production and protein degradation during ripening. Apple cDNA and oligonucleotide microarrays have been generated for more comprehensive examinations. Such tools are powerful means for elucidating the molecular events involved in metabolite biosynthesis and physiological changes and will also enable researchers to understand how to control that ripening process.

Original languageEnglish
Pages (from-to)35-40
Number of pages6
JournalJournal of Plant Biology
Issue number1
Publication statusPublished - 2009 Feb

Bibliographical note

Funding Information:
Acknowledgments This work was supported in part by grants to W. T.K. from the Plant Diversity Research Center (21st Century Frontier Research Program funded by the Ministry of Education, Science and Technology), the BioGreen 21 Program (funded by Rural Development Administration), and the Plant Metabolism Research Center at Kyung Hee University (Science Research Center Project No. R11-2000-081 from the Korea Science and Engineering Foundation). Y.S. S. was the recipient of a BK21 post-doctoral scholarship.

All Science Journal Classification (ASJC) codes

  • Plant Science


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