A deeper convolutional neural network for denoising low-dose CT images

Byeongjoon Kim, Hyunjung Shim, Jongduk Baek

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)


In recent years, CNN has been gaining attention as a powerful denoising tool after the pioneering work [7], developing 3-layer convolutional neural network (CNN). However, the 3-layer CNN may lose details or contrast after denoising due to its shallow depth. In this study, we propose a deeper, 7-layer CNN for denoising low-dose CT images. We introduced dimension shrinkage and expansion steps to control explosion of the number of parameters, and also applied the batch normalization to alleviate difficulty in optimization. The network was trained and tested with Shepp-Logan phantom images reconstructed by FBP algorithm from projection data generated in a fan-beam geometry. For a training set and a test set, the independently generated uniform noise with different noise levels was added to the projection data. The image quality improvement was evaluated both qualitatively and quantitatively, and the results show that the proposed CNN effectively reduces the noise without resolution loss compared to BM3D and the 3-layer CNN.

Original languageEnglish
Title of host publicationMedical Imaging 2018
Subtitle of host publicationPhysics of Medical Imaging
EditorsTaly Gilat Schmidt, Guang-Hong Chen, Joseph Y. Lo
ISBN (Electronic)9781510616356
Publication statusPublished - 2018
EventMedical Imaging 2018: Physics of Medical Imaging - Houston, United States
Duration: 2018 Feb 122018 Feb 15

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherMedical Imaging 2018: Physics of Medical Imaging
Country/TerritoryUnited States

Bibliographical note

Funding Information:
This research was supported by the MSIP (Ministry of Science, ICT and Future Planning), Korea, under the “ICT Consilience Creative Program” (IITP-R0346-16-1008) supervised by the IITP (Institute for Information & communications Technology Promotion)

Publisher Copyright:
© 2018 SPIE.

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging


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