A concise synthesis of (-)-cytoxazone

Van Thoai Pham; Jae Eun Joo; Yong Shou Tian; Yong Hyun Kim; Kee Young Lee; Chang Young Oh; Jin Hyun Jeong; Won Hun Ham

doi:10.3987/COM-08-11446

A concise synthesis of (-)-cytoxazone

Van Thoai Pham, Jae Eun Joo, Yong Shou Tian, Yong Hyun Kim, Kee Young Lee, Chang Young Oh, Jin Hyun Jeong, Won Hun Ham

Department of Pharmacy

Research output: Contribution to journal › Review article › peer-review

3 Citations (Scopus)

Abstract

A concise, stereoselective synthesis of (-)-cytoxazone 1 was described. A key feature is highly diastereoselective reduction of the amino ketone to give the anti-amino alcohol directly, which is 2-oxazolidinone precursor.

Original language	English
Pages (from-to)	2817-2823
Number of pages	7
Journal	Heterocycles
Volume	75
Issue number	11
DOIs	https://doi.org/10.3987/COM-08-11446
Publication status	Published - 2008

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Pharmacology
Organic Chemistry

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10.3987/COM-08-11446

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title = "A concise synthesis of (-)-cytoxazone",

abstract = "A concise, stereoselective synthesis of (-)-cytoxazone 1 was described. A key feature is highly diastereoselective reduction of the amino ketone to give the anti-amino alcohol directly, which is 2-oxazolidinone precursor.",

author = "Pham, {Van Thoai} and Joo, {Jae Eun} and Tian, {Yong Shou} and Kim, {Yong Hyun} and Lee, {Kee Young} and Oh, {Chang Young} and Jeong, {Jin Hyun} and Ham, {Won Hun}",

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doi = "10.3987/COM-08-11446",

language = "English",

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publisher = "Japan Institute of Heterocyclic Chemistry",

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T1 - A concise synthesis of (-)-cytoxazone

AU - Pham, Van Thoai

AU - Joo, Jae Eun

AU - Tian, Yong Shou

AU - Kim, Yong Hyun

AU - Lee, Kee Young

AU - Oh, Chang Young

AU - Jeong, Jin Hyun

AU - Ham, Won Hun

PY - 2008

Y1 - 2008

N2 - A concise, stereoselective synthesis of (-)-cytoxazone 1 was described. A key feature is highly diastereoselective reduction of the amino ketone to give the anti-amino alcohol directly, which is 2-oxazolidinone precursor.

AB - A concise, stereoselective synthesis of (-)-cytoxazone 1 was described. A key feature is highly diastereoselective reduction of the amino ketone to give the anti-amino alcohol directly, which is 2-oxazolidinone precursor.

UR - http://www.scopus.com/inward/record.url?scp=76749139655&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=76749139655&partnerID=8YFLogxK

U2 - 10.3987/COM-08-11446

DO - 10.3987/COM-08-11446

M3 - Review article

AN - SCOPUS:76749139655

SN - 0385-5414

VL - 75

SP - 2817

EP - 2823

JO - Heterocycles

JF - Heterocycles

IS - 11

ER -

A concise synthesis of (-)-cytoxazone

Abstract

All Science Journal Classification (ASJC) codes

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