A concise synthesis and in vitro cytotoxicity of new labdane diterpenes

Mankil Jung; Imju Ko; Seokjoon Lee; Sun Ju Choi; Byoung Hee Youn; Soo Kie Kim

doi:10.1016/S0960-894X(98)00603-9

A concise synthesis and in vitro cytotoxicity of new labdane diterpenes

Mankil Jung, Imju Ko, Seokjoon Lee, Sun Ju Choi, Byoung Hee Youn, Soo Kie Kim

Microbiology

Research output: Contribution to journal › Article › peer-review

39 Citations (Scopus)

Abstract

A new series of labdane-related diterpenes have been synthesized from (- )-sclareoi and assayed in vitro cytotoxicity against mouse and human cancer cells. A key intermediate, homodrimane and furanolabdane derivatives show good in vitro cytotoxicity comparable to those of mitomycin C and adriamycin.

Original language	English
Pages (from-to)	3295-3298
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	8
Issue number	23
DOIs	https://doi.org/10.1016/S0960-894X(98)00603-9
Publication status	Published - 1998 Dec 1

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0960-894X(98)00603-9

Cite this

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abstract = "A new series of labdane-related diterpenes have been synthesized from (- )-sclareoi and assayed in vitro cytotoxicity against mouse and human cancer cells. A key intermediate, homodrimane and furanolabdane derivatives show good in vitro cytotoxicity comparable to those of mitomycin C and adriamycin.",

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AU - Youn, Byoung Hee

AU - Kim, Soo Kie

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A concise synthesis and in vitro cytotoxicity of new labdane diterpenes

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

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