A case of Tsutsugamushi disease presenting with nephrotic syndrome

Ju Hyun Lee, Mi Jung Lee, Dong Ho Shin, Shin Wook Kang, Kyu Hun Choi, Tae Hyun Yoo

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Nephrotic syndrome associated with Tsutsugamushi disease has not been previously reported. We are describing a case of Tsutsugamuchi disease presenting with nephrotic syndrome. A 72-year-old woman presented with fever and generalized edema. Laboratory studies revealed a leukocytosis, hypoalbuminemia, and hypercholesterolemia. Her urine protein excretion was 5.4 g/day. The anti- Tsutsugamushi antibody test was strongly positive (1:2,560). A renal biopsy was performed, and pathologic findings revealed membranous glomerulonephritis. The patient's clinical symptoms improved markedly after treatment with doxycycline.

Original languageEnglish
Pages (from-to)728-731
Number of pages4
JournalKorean Journal of Internal Medicine
Issue number6
Publication statusPublished - 2013 Nov

All Science Journal Classification (ASJC) codes

  • Internal Medicine


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