A case of pentastomiasis at the left maxilla bone in a patient with thyroid cancer

Eunae Sandra Cho, Seung Wook Jung, Hwi Dong Jung, In Yong Lee, Tai Soon Yong, Su Jin Jeong, Hyun Sil Kim

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2 Citations (Scopus)


Pentastomiasis, a zoonotic parasite infection, is typically found in the respiratory tract and viscera of the host, including humans. Here, we report for the first time an extremely rare case of intraosseous pentastomiasis in the human maxilla suffering from medication related osteonecrosis of the jaw (MRONJ). A 55-year-old male had continuously visited the hospital for MRONJ which had primarily developed after bisphosphonate and anti-neoplastic administration for previous bone metastasis of medullary thyroid cancer. Pain, bone exposure, and pus discharge in the right mandible and left maxilla were seen. Osteolysis with maxillary cortical bone perforation at the left buccal vestibule, palate, nasal cavity, and maxillary sinus was observed by radiologic images. A biopsy was done at the left maxilla and through pathological evaluation, a parasite with features of pentastome was revealed within the necrotic bone tissue. Further history taking and laboratory evaluation was done. The parasite was suspected to be infected through maxillary open wounds caused by MRONJ. Awareness of intraosseous pentastomiasis should be emphasized not to be missed behind the MRONJ. Proper evaluation and interpretation for past medical history may lead to correct differential diagnosis and therapeutic intervention for parasite infections.

Original languageEnglish
Pages (from-to)433-437
Number of pages5
JournalKorean Journal of Parasitology
Issue number4
Publication statusPublished - 2017 Aug

Bibliographical note

Funding Information:
This work was supported by grants from the National Research Foundation of Korea (NRF-2017R1C1B1012464, NRF-2016R1E1A1A01942724) funded by the Korea government (MSIP) and a grant from the National Research Foundation of Korea (NRF-2014R1A6A3A04055110) funded by the Korea government (MOE).

Publisher Copyright:
© 2017, Korean Society for Parasitology and Tropical Medicine.

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Infectious Diseases


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