A case of multiple endocrine neoplasia type 1 combined with papillary thyroid carcinoma

Hai Jin Kim; Jong Suk Park; Chul Sik Kim; Eun Seok Kang; Bong Soo Cha; Sung Kil Lim; Kyung Rae Kim; Hyun Chul Lee; Chul Woo Ahn

doi:10.3349/ymj.2008.49.3.503

A case of multiple endocrine neoplasia type 1 combined with papillary thyroid carcinoma

Hai Jin Kim, Jong Suk Park, Chul Sik Kim, Eun Seok Kang, Bong Soo Cha, Sung Kil Lim, Kyung Rae Kim, Hyun Chul Lee, Chul Woo Ahn

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

This is the first report of papillary thyroid carcinoma combined with multiple endocrine neoplasia type I (MEN 1) in Korea. MEN1 is a hereditary disease comprising neoplastic disorders such as pituitary, parathyroid and pancreatic neuroendocrine tumor, such as gastrinoma. But papillary thyroid cancer was never regarded as its component before in Korea. Herein we present a 39-year-old woman who manifested typical features of MEN1 with a coincidental papillary thyroid carcinoma. Although the family history of MEN1 was definite, her genetic analysis of DNA had revealed no germline mutation in MEN1 gene locus. Unidentified culprit gene unable us further genetic study to find LOH (loss of heterogeneity) in 11q13, the possible explanation of papillary thyroid carcinoma as a new component of MEN1. As we have first experienced a case of MEN1 combined with papillary thyroid carcinoma in Korea, we report it with the review of literature.

Original language	English
Pages (from-to)	503-506
Number of pages	4
Journal	Yonsei medical journal
Volume	49
Issue number	3
DOIs	https://doi.org/10.3349/ymj.2008.49.3.503
Publication status	Published - 2008 Jun

All Science Journal Classification (ASJC) codes

Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3349/ymj.2008.49.3.503

Cite this

@article{047adeb10704451ab231b0fdf7a00f28,

title = "A case of multiple endocrine neoplasia type 1 combined with papillary thyroid carcinoma",

abstract = "This is the first report of papillary thyroid carcinoma combined with multiple endocrine neoplasia type I (MEN 1) in Korea. MEN1 is a hereditary disease comprising neoplastic disorders such as pituitary, parathyroid and pancreatic neuroendocrine tumor, such as gastrinoma. But papillary thyroid cancer was never regarded as its component before in Korea. Herein we present a 39-year-old woman who manifested typical features of MEN1 with a coincidental papillary thyroid carcinoma. Although the family history of MEN1 was definite, her genetic analysis of DNA had revealed no germline mutation in MEN1 gene locus. Unidentified culprit gene unable us further genetic study to find LOH (loss of heterogeneity) in 11q13, the possible explanation of papillary thyroid carcinoma as a new component of MEN1. As we have first experienced a case of MEN1 combined with papillary thyroid carcinoma in Korea, we report it with the review of literature.",

author = "Kim, {Hai Jin} and Park, {Jong Suk} and Kim, {Chul Sik} and Kang, {Eun Seok} and Cha, {Bong Soo} and Lim, {Sung Kil} and Kim, {Kyung Rae} and Lee, {Hyun Chul} and Ahn, {Chul Woo}",

year = "2008",

month = jun,

doi = "10.3349/ymj.2008.49.3.503",

language = "English",

volume = "49",

pages = "503--506",

journal = "Yonsei Medical Journal",

issn = "0513-5796",

publisher = "Yonsei University College of Medicine",

number = "3",

}

TY - JOUR

T1 - A case of multiple endocrine neoplasia type 1 combined with papillary thyroid carcinoma

AU - Kim, Hai Jin

AU - Park, Jong Suk

AU - Kim, Chul Sik

AU - Kang, Eun Seok

AU - Cha, Bong Soo

AU - Lim, Sung Kil

AU - Kim, Kyung Rae

AU - Lee, Hyun Chul

AU - Ahn, Chul Woo

PY - 2008/6

Y1 - 2008/6

N2 - This is the first report of papillary thyroid carcinoma combined with multiple endocrine neoplasia type I (MEN 1) in Korea. MEN1 is a hereditary disease comprising neoplastic disorders such as pituitary, parathyroid and pancreatic neuroendocrine tumor, such as gastrinoma. But papillary thyroid cancer was never regarded as its component before in Korea. Herein we present a 39-year-old woman who manifested typical features of MEN1 with a coincidental papillary thyroid carcinoma. Although the family history of MEN1 was definite, her genetic analysis of DNA had revealed no germline mutation in MEN1 gene locus. Unidentified culprit gene unable us further genetic study to find LOH (loss of heterogeneity) in 11q13, the possible explanation of papillary thyroid carcinoma as a new component of MEN1. As we have first experienced a case of MEN1 combined with papillary thyroid carcinoma in Korea, we report it with the review of literature.

AB - This is the first report of papillary thyroid carcinoma combined with multiple endocrine neoplasia type I (MEN 1) in Korea. MEN1 is a hereditary disease comprising neoplastic disorders such as pituitary, parathyroid and pancreatic neuroendocrine tumor, such as gastrinoma. But papillary thyroid cancer was never regarded as its component before in Korea. Herein we present a 39-year-old woman who manifested typical features of MEN1 with a coincidental papillary thyroid carcinoma. Although the family history of MEN1 was definite, her genetic analysis of DNA had revealed no germline mutation in MEN1 gene locus. Unidentified culprit gene unable us further genetic study to find LOH (loss of heterogeneity) in 11q13, the possible explanation of papillary thyroid carcinoma as a new component of MEN1. As we have first experienced a case of MEN1 combined with papillary thyroid carcinoma in Korea, we report it with the review of literature.

UR - http://www.scopus.com/inward/record.url?scp=48649107644&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=48649107644&partnerID=8YFLogxK

U2 - 10.3349/ymj.2008.49.3.503

DO - 10.3349/ymj.2008.49.3.503

M3 - Article

C2 - 18581603

AN - SCOPUS:48649107644

SN - 0513-5796

VL - 49

SP - 503

EP - 506

JO - Yonsei Medical Journal

JF - Yonsei Medical Journal

IS - 3

ER -

A case of multiple endocrine neoplasia type 1 combined with papillary thyroid carcinoma

Abstract

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this