Localized scleroderma is a connective tissue disorder that's characterized by thickening and fibrosis of the skin due to excessive collagen deposition. Localized scleroderma differs from systemic sclerosis according to the absence of Raynaud's phenomenon, sclerodactyly or systemic involvement. Dystrophic calcinosis cutis occurs in up to 10% of the patients with systemic sclerosis, but it is rare in localized scleroderma. Only seven cases of localized scleroderma with calcinosis cutis have been reported in the English medical literature. We report here on a 57-year-old woman with localized scleroderma with dystrophic calcification, and this was identified by the histopathology and CT scans. The serologic tests for the autoimmune antibodies anti-RNP, ENA and anti-SS-A(Ro) were all positive. (Korean J Dermatol 2008;46(10):1442-1444).
|Number of pages
|Korean Journal of Dermatology
|Published - 2008 Oct
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