A benzthiazole-based tripodal chemosensor for Ba2+ recognition under biological conditions

Preeti Saluja; Navneet Kaur; Narinder Singh; Doo Ok Jang

doi:10.1016/j.tetlet.2011.09.132

A benzthiazole-based tripodal chemosensor for Ba²⁺ recognition under biological conditions

Preeti Saluja, Navneet Kaur, Narinder Singh, Doo Ok Jang

Chemistry and Medical Chemistry

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

We synthesized a benzthiazole-based chemosensor with mixed S,N donor sites. The binding units are incorporated in a highly flexible tripodal framework which facilitates the complexation of the binding of larger-sized metals. The chemosensor resulted in the sensitive and selective recognition of Ba ²⁺ through the enhancement of the fluorescence intensity when studied in a THF/H₂O (8:2, v/v) solvent mixture. The sensor offers an interesting opportunity to monitor Ba²⁺ in biological samples including the cytoplasm of microbes such as Saccharomyces cerevisiae.

Original language	English
Pages (from-to)	6705-6708
Number of pages	4
Journal	Tetrahedron Letters
Volume	52
Issue number	50
DOIs	https://doi.org/10.1016/j.tetlet.2011.09.132
Publication status	Published - 2011 Dec 14

Bibliographical note

Funding Information:
This work was supported by an India–Korea Joint Program of Cooperation in Science &Technology, an ISIRD grant from IIT Ropar, and the CBMH. PS is thankful to the UGC India for a research fellowship. We thank Mr. S. Soni of CSIO Chandigarh for fluorescence microscopy assistance.

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2011.09.132

Cite this

@article{c68079cc700a4169bfc556ea885cd9b2,

title = "A benzthiazole-based tripodal chemosensor for Ba2+ recognition under biological conditions",

abstract = "We synthesized a benzthiazole-based chemosensor with mixed S,N donor sites. The binding units are incorporated in a highly flexible tripodal framework which facilitates the complexation of the binding of larger-sized metals. The chemosensor resulted in the sensitive and selective recognition of Ba 2+ through the enhancement of the fluorescence intensity when studied in a THF/H2O (8:2, v/v) solvent mixture. The sensor offers an interesting opportunity to monitor Ba2+ in biological samples including the cytoplasm of microbes such as Saccharomyces cerevisiae.",

author = "Preeti Saluja and Navneet Kaur and Narinder Singh and Jang, {Doo Ok}",

note = "Funding Information: This work was supported by an India–Korea Joint Program of Cooperation in Science &Technology, an ISIRD grant from IIT Ropar, and the CBMH. PS is thankful to the UGC India for a research fellowship. We thank Mr. S. Soni of CSIO Chandigarh for fluorescence microscopy assistance. ",

year = "2011",

month = dec,

day = "14",

doi = "10.1016/j.tetlet.2011.09.132",

language = "English",

volume = "52",

pages = "6705--6708",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "50",

}

TY - JOUR

T1 - A benzthiazole-based tripodal chemosensor for Ba2+ recognition under biological conditions

AU - Saluja, Preeti

AU - Kaur, Navneet

AU - Singh, Narinder

AU - Jang, Doo Ok

N1 - Funding Information: This work was supported by an India–Korea Joint Program of Cooperation in Science &Technology, an ISIRD grant from IIT Ropar, and the CBMH. PS is thankful to the UGC India for a research fellowship. We thank Mr. S. Soni of CSIO Chandigarh for fluorescence microscopy assistance.

PY - 2011/12/14

Y1 - 2011/12/14

N2 - We synthesized a benzthiazole-based chemosensor with mixed S,N donor sites. The binding units are incorporated in a highly flexible tripodal framework which facilitates the complexation of the binding of larger-sized metals. The chemosensor resulted in the sensitive and selective recognition of Ba 2+ through the enhancement of the fluorescence intensity when studied in a THF/H2O (8:2, v/v) solvent mixture. The sensor offers an interesting opportunity to monitor Ba2+ in biological samples including the cytoplasm of microbes such as Saccharomyces cerevisiae.

AB - We synthesized a benzthiazole-based chemosensor with mixed S,N donor sites. The binding units are incorporated in a highly flexible tripodal framework which facilitates the complexation of the binding of larger-sized metals. The chemosensor resulted in the sensitive and selective recognition of Ba 2+ through the enhancement of the fluorescence intensity when studied in a THF/H2O (8:2, v/v) solvent mixture. The sensor offers an interesting opportunity to monitor Ba2+ in biological samples including the cytoplasm of microbes such as Saccharomyces cerevisiae.

UR - http://www.scopus.com/inward/record.url?scp=80755135451&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80755135451&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2011.09.132

DO - 10.1016/j.tetlet.2011.09.132

M3 - Article

AN - SCOPUS:80755135451

SN - 0040-4039

VL - 52

SP - 6705

EP - 6708

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 50

ER -