11.3 A Capacitive Biosensor for Cancer Diagnosis Using a Functionalized Microneedle and a 13.7b-Resolution Capacitance-to-Digital Converter from 1 to 100nF

Seungwoo Song; Jukwan Na; Moonhyung Jang; Hyeyeon Lee; Hyesoo Lee; Yongbeom Lim; Heonjin Choi; Youngcheol Chae

doi:10.1109/ISSCC.2019.8662522

11.3 A Capacitive Biosensor for Cancer Diagnosis Using a Functionalized Microneedle and a 13.7b-Resolution Capacitance-to-Digital Converter from 1 to 100nF

Seungwoo Song, Jukwan Na, Moonhyung Jang, Hyeyeon Lee, Hyesoo Lee, Yongbeom Lim, Heonjin Choi, Youngcheol Chae

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Citations (Scopus)

Abstract

A malignant tumor consists of rapidly growing cancer cells, and requires a dedicated blood supply to provide oxygen and nutrients. Therefore, vascular endothelial growth factor (VEGF), a signal protein produced by cells stimulating angiogenesis, is considered as a key biomarker in clinical diagnosis of cancers [1], [2]. There are already existing methods for the VEGF detection requiring advanced instruments and complex protocols [2]. Recently, significant progress has been achieved in biosensors for the detection and quantification of VEGF using synthetic receptors [2]. In particular, a capacitive biosensor detects the change of dielectric properties when the receptor binds to VEGF, and capacitance change can be used to quantify the reactions. However, the sensitivity of the capacitive biosensors still needs to be improved for use in cancer diagnosis.

Original language	English
Title of host publication	2019 IEEE International Solid-State Circuits Conference, ISSCC 2019
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	194-196
Number of pages	3
ISBN (Electronic)	9781538685310
DOIs	https://doi.org/10.1109/ISSCC.2019.8662522
Publication status	Published - 2019 Mar 6
Event	2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 - San Francisco, United States Duration: 2019 Feb 17 → 2019 Feb 21

Publication series

Name	Digest of Technical Papers - IEEE International Solid-State Circuits Conference
Volume	2019-February
ISSN (Print)	0193-6530

Conference

Conference	2019 IEEE International Solid-State Circuits Conference, ISSCC 2019
Country/Territory	United States
City	San Francisco
Period	19/2/17 → 19/2/21

Bibliographical note

Publisher Copyright:
© 2019 IEEE.

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Electrical and Electronic Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1109/ISSCC.2019.8662522

Cite this

Song, S., Na, J., Jang, M., Lee, H., Lee, H., Lim, Y., Choi, H., & Chae, Y. (2019). 11.3 A Capacitive Biosensor for Cancer Diagnosis Using a Functionalized Microneedle and a 13.7b-Resolution Capacitance-to-Digital Converter from 1 to 100nF. In 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 (pp. 194-196). Article 8662522 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; Vol. 2019-February). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ISSCC.2019.8662522

Song, Seungwoo ; Na, Jukwan ; Jang, Moonhyung et al. / 11.3 A Capacitive Biosensor for Cancer Diagnosis Using a Functionalized Microneedle and a 13.7b-Resolution Capacitance-to-Digital Converter from 1 to 100nF. 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. pp. 194-196 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference).

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title = "11.3 A Capacitive Biosensor for Cancer Diagnosis Using a Functionalized Microneedle and a 13.7b-Resolution Capacitance-to-Digital Converter from 1 to 100nF",

abstract = "A malignant tumor consists of rapidly growing cancer cells, and requires a dedicated blood supply to provide oxygen and nutrients. Therefore, vascular endothelial growth factor (VEGF), a signal protein produced by cells stimulating angiogenesis, is considered as a key biomarker in clinical diagnosis of cancers [1], [2]. There are already existing methods for the VEGF detection requiring advanced instruments and complex protocols [2]. Recently, significant progress has been achieved in biosensors for the detection and quantification of VEGF using synthetic receptors [2]. In particular, a capacitive biosensor detects the change of dielectric properties when the receptor binds to VEGF, and capacitance change can be used to quantify the reactions. However, the sensitivity of the capacitive biosensors still needs to be improved for use in cancer diagnosis.",

author = "Seungwoo Song and Jukwan Na and Moonhyung Jang and Hyeyeon Lee and Hyesoo Lee and Yongbeom Lim and Heonjin Choi and Youngcheol Chae",

note = "Publisher Copyright: {\textcopyright} 2019 IEEE.; 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019 ; Conference date: 17-02-2019 Through 21-02-2019",

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Song, S, Na, J, Jang, M, Lee, H, Lee, H, Lim, Y , Choi, H & Chae, Y 2019, 11.3 A Capacitive Biosensor for Cancer Diagnosis Using a Functionalized Microneedle and a 13.7b-Resolution Capacitance-to-Digital Converter from 1 to 100nF. in 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019., 8662522, Digest of Technical Papers - IEEE International Solid-State Circuits Conference, vol. 2019-February, Institute of Electrical and Electronics Engineers Inc., pp. 194-196, 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019, San Francisco, United States, 19/2/17. https://doi.org/10.1109/ISSCC.2019.8662522

11.3 A Capacitive Biosensor for Cancer Diagnosis Using a Functionalized Microneedle and a 13.7b-Resolution Capacitance-to-Digital Converter from 1 to 100nF. / Song, Seungwoo; Na, Jukwan; Jang, Moonhyung et al.
2019 IEEE International Solid-State Circuits Conference, ISSCC 2019. Institute of Electrical and Electronics Engineers Inc., 2019. p. 194-196 8662522 (Digest of Technical Papers - IEEE International Solid-State Circuits Conference; Vol. 2019-February).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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Song S, Na J, Jang M, Lee H, Lee H, Lim Y et al. 11.3 A Capacitive Biosensor for Cancer Diagnosis Using a Functionalized Microneedle and a 13.7b-Resolution Capacitance-to-Digital Converter from 1 to 100nF. In 2019 IEEE International Solid-State Circuits Conference, ISSCC 2019. Institute of Electrical and Electronics Engineers Inc. 2019. p. 194-196. 8662522. (Digest of Technical Papers - IEEE International Solid-State Circuits Conference). doi: 10.1109/ISSCC.2019.8662522

11.3 A Capacitive Biosensor for Cancer Diagnosis Using a Functionalized Microneedle and a 13.7b-Resolution Capacitance-to-Digital Converter from 1 to 100nF

Abstract

Publication series

Conference

Bibliographical note

All Science Journal Classification (ASJC) codes

UN SDGs

Access to Document

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