Interdisciplinary Program of Integrated OMICS for Biomedical Sciences

Research output

Research output per year 1981 1998 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2022 2023

• 658 Article
• 59 Review article
• 13 Chapter
• 9 Comment/debate
• 15 More
  • 5 Editorial
  • 5 Letter
  • 2 Conference contribution
  • 2 Short survey
  • 1 Paper

Research output per year

Research output per year

Search results

• 2023

  Personalised circulating tumour DNA assay with large-scale mutation coverage for sensitive minimal residual disease detection in colorectal cancer

  Ryoo, S. B., Heo, S., Lim, Y., Lee, W., Cho, S. H., Ahn, J., Kang, J. K., Kim, S. Y., Kim, H. P., Bang, D., Kang, S. B., Yu, C. S., Oh, S. T., Park, J. W., Jeong, S. Y., Kim, Y. J., Park, K. J., Han, S. W. & Kim, T. Y., 2023 Aug 10, In: British journal of cancer. 129, 2, p. 374-381 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Colorectal Cancer 100%
  • Minimal Residual Disease 100%
  • DNA Determination 100%
  • Circulating Tumor DNA 100%
  • Patient 60%

• Structural optimization of novel Ras modulator for treatment of Colorectal cancer by promoting β-catenin and Ras degradation

  Choi, S., Kim, H., Ryu, W. J., Choi, K. Y., Kim, T., Song, D. & Han, G., 2023 Jan, In: Bioorganic Chemistry. 130, 106234.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ras 100%
  • Catenin 50%
  • Development 25%
  • Cancer Treatment 25%
  • Mechanism of Action 25%
• 2022

  2′–5′ oligoadenylate synthetase‑like 1 (OASL1) protects against atherosclerosis by maintaining endothelial nitric oxide synthase mRNA stability

  Kim, T. K., Jeon, S., Park, S., Sonn, S. K., Seo, S., Suh, J., Jin, J., Kweon, H. Y., Kim, S., Moon, S. H., Kweon, O., Koo, B. H., Kim, N., Lee, H. O., Kim, Y. M., Kim, Y. J., Park, S. H. & Oh, G. T., 2022 Dec, In: Nature communications. 13, 1, 6647.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Endothelial Nitric Oxide Synthase 100%
  • Nitric Oxide Synthase 100%
  • Messenger RNA 50%
  • mRNA Stability 25%
  • Bioavailability 12%
  4 Citations (Scopus)

• A database of 5305 healthy Korean individuals reveals genetic and clinical implications for an East Asian population

  Lee, J., Lee, J., Jeon, S., Lee, J., Jang, I., Yang, J. O., Park, S., Lee, B., Choi, J., Choi, B. O., Gee, H. Y., Oh, J., Jang, I. J., Lee, S., Baek, D., Koh, Y., Yoon, S. S., Kim, Y. J., Chae, J. H., Park, W. Y., & 2 othersBhak, J. H. & Choi, M., 2022 Nov, In: Experimental and Molecular Medicine. 54, 11, p. 1862-1871 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Data Base 100%
  • Genetics 100%
  • Age 66%
  • Allele 33%
  • Genetic Divergence 33%
  1 Citation (Scopus)

• A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut-liver axis and microbiome

  Kim, E. R., Park, J. S., Kim, J. H., Oh, J. Y., Oh, IJ., Choi, D. H., Lee, Y. S., Park, I. S., Kim, S. W., Lee, D. H., Cheon, J. H., Bae, J. W., Lee, M., Cho, J. W., An, I. B., Nam, E. J., Yang, S. I., Lee, M. S., Bae, S. H. & Lee, Y. H., 2022 Jun, In: Hepatology. 75, 6, p. 1523-1538 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Agonist 100%
  • Non-Alcoholic Fatty Liver Disease 66%
  • Liver Fibrosis 50%
  • Microbiome 50%
  • Glucagon Like Peptide 1 50%
  19 Citations (Scopus)

• Amino acid metabolism in cancer drug resistance

  Yoo, H. C. & Han, J. M., 2022 Jan 1, In: Cells. 11, 1, 140.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Amino Acid Metabolism 100%
  • Drug Resistance in Cancer 100%
  • Drug Resistance 100%
  • Combination Therapy 75%
  • Cancer Cell 75%
  24 Citations (Scopus)

• An O-GlcNAcase responsive fluorogenic probe for biological applications

  Jung, H., Park, S. H., Yang, W. H., Cho, J. W. & Shin, I., 2022 Sept 15, In: Sensors and Actuators B: Chemical. 367, 132093.

  Research output: Contribution to journal › Article › peer-review

  • Probe 100%
  • Glucose 40%
  • Concentration 40%
  • Fluorescence 20%
  • Fluorescence Intensity 20%
  1 Citation (Scopus)

• Association of Metabolomic Change and Treatment Response in Patients with Non-Alcoholic Fatty Liver Disease

  Lee, K. S., Cho, Y., Kim, H., Hwang, H., Cho, J. W., Lee, Y. H. & Lee, S. G., 2022 Jun, In: Biomedicines. 10, 6, 1216.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Nonalcoholic Fatty Liver 100%
  • Fatty Liver 75%
  • Rigidity 75%
  • Fat 75%
  • Diseases 50%
  2 Citations (Scopus)

• Author Correction: O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine (Nature Communications, (2022), 13, 1, (2904), 10.1038/s41467-022-30696-8)

  Kim, K., Yoo, H. C., Kim, B. G., Kim, S., Sung, Y., Yoon, I., Yu, Y. C., Park, S. J., Kim, J. H., Myung, K., Hwang, K. Y., Kim, S. & Han, J. M., 2022 Dec, In: Nature communications. 13, 1, 6253.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Leucine 100%
  • Glucose 50%
  • Error 50%
  • Immunoblotting 50%
  • Leucine Transfer RNA Ligase 50%

• Brite Adipocyte FGF21 Attenuates Cardiac Ischemia/ Reperfusion Injury in Rat Hearts by Modulating NRF2

  Moon, H., Choi, J. W., Song, B. W., Kim, I. K., Lim, S., Lee, S., Han, G., Hwang, K. C. & Kim, S. W., 2022 Feb 1, In: Cells. 11, 3, 567.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Beige Adipocyte 100%
  • Antiapoptotic 88%
  • FGF21 55%
  • Fibroblast Growth Factor 21 55%
  • Cardiomyocyte 44%
  3 Citations (Scopus)

• Deficiency in RCAT-1 Function Causes Dopamine Metabolism Related Behavioral Disorders in Caenorhabditis elegans

  Jeong, H., Park, J. Y., Lee, J. H., Baik, J. H., Kim, C. Y., Cho, J. Y., Driscoll, M. & Paik, Y. K., 2022 Feb 1, In: International journal of molecular sciences. 23, 4, 2393.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene 100%
  • Dopamine 44%
  • Locomotion 44%
  • Behavior Disorder 22%
  • Behavior (Neuroscience) 22%

• Euodia daniellii Hemsl. Extract and Its Active Component Hesperidin Accelerate Cutaneous Wound Healing via Activation of Wnt/β-Catenin Signaling Pathway

  Yoon, M., Seo, S. H., Choi, S., Han, G. & Choi, K. Y., 2022 Oct, In: Molecules. 27, 20, 7134.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Wound Healing 100%
  • Catenin 75%
  • Hesperidin 37%
  • Skin Injury 25%
  • Collagen 12%
  1 Citation (Scopus)

• Functional and pathologic association of aminoacyl-tRNA synthetases with cancer

  Sung, Y., Yoon, I., Han, J. M. & Kim, S., 2022 May, In: Experimental and Molecular Medicine. 54, 5, p. 553-566 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Malignant Neoplasm 100%
  • Synthetase 71%
  • Aminoacyl Transfer RNA 71%
  • Synthase 71%
  • Aminoacyl-tRNA 71%
  6 Citations (Scopus)

• Indirubin-3′-alkoxime derivatives for upregulation of Wnt signaling through dual inhibition of GSK-3β and the CXXC5-Dvl interaction

  Song, D., Lee, Y., Kang, M. J., Won Kim, J., Lee, S. H., Choi, K. Y., Kim, E. Y., Lee, K. & Han, G., 2022 Apr, In: Bioorganic Chemistry. 121, 105664.

  Research output: Contribution to journal › Article › peer-review

  • Glycogen Synthase Kinase 3 100%
  • Dishevelled 85%
  • Dishevelled Protein 85%
  • Wnt Signaling Pathway 57%
  • Wnt Signaling 57%
  1 Citation (Scopus)

• Inhibition of phospholipase D1 induces immunogenic cell death and potentiates cancer immunotherapy in colorectal cancer

  Hwang, W. C., Song, D., Lee, H., Oh, C., Lim, S. H., Bae, H. J., Kim, N. D., Han, G. & Min, D. S., 2022 Sept, In: Experimental and Molecular Medicine. 54, 9, p. 1563-1576 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Programmed Cell Death 100%
  • Colorectal Cancer 75%
  • Cancer Cell 62%
  • Combination Therapy 37%
  • Neoplasm 25%
  2 Citations (Scopus)

• Mast4 determines the cell fate of MSCs for bone and cartilage development

  Kim, P., Park, J., Lee, D. J., Mizuno, S., Shinohara, M., Hong, C. P., Jeong, Y., Yun, R., Park, H., Park, S., Yang, K. M., Lee, M. J., Jang, S. P., Kim, H. Y., Lee, S. J., Song, S. U., Park, K. S., Tanaka, M., Ohshima, H., Cho, J. W., & 4 othersSugiyama, F., Takahashi, S., Jung, H. S. & Kim, S. J., 2022 Dec, In: Nature communications. 13, 1, 3960.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Stromal Cell 100%
  • Serine 28%
  • Signal Transduction 28%
  • Bone 28%
  • Degradation 14%
  11 Citations (Scopus)

• Methylation-sensitive high-resolution melting analysis of the USP44 promoter can detect early-stage hepatocellular carcinoma in blood samples

  Kim, S. C., Kim, J., Kim, D. W., Choi, Y., Park, K., Cho, E. J., Yu, S. J., Kim-Ha, J. & Kim, Y. J., 2022, In: BMB reports. 55, 11, p. 553-558 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Methylation 100%
  • Melting Point 66%
  • Promoter Region 50%
  • Data Base 16%
  • CpG Island 16%

• Nephrin expression in human epidermal keratinocytes and its implication in poor wound closure

  Kim, J. Y., Lee, E. J., Seo, J., Lee, Y., Ahn, Y., Park, S., Bae, Y. J., Lee, J., Lim, B. J., Kim, D., Cho, J. W. & Oh, S. H., 2022 Jul, In: FASEB Journal. 36, 7, e22424.

  Research output: Contribution to journal › Article › peer-review

  • Nephrin 100%
  • Keratinocyte 58%
  • Cell Migration 33%
  • Skin 33%
  • Cell Proliferation 16%
  1 Citation (Scopus)

• OASL1-Mediated Inhibition of Type I IFN Reduces Influenza A Infection-Induced Airway Inflammation by Regulating ILC2s

  Chang, Y., Kang, J. S., Jung, K., Chung, D. H., Ha, S. J., Kim, Y. J. & Kim, H. Y., 2022 Jan, In: Allergy, Asthma and Immunology Research. 14, 1, p. 99-116 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Interferon Type I 100%
  • Influenza A Virus 50%
  • Lung 50%
  • Influenzavirus A 50%
  • Asthma 42%
  2 Citations (Scopus)

• O-GlcNAc modification of leucyl-tRNA synthetase 1 integrates leucine and glucose availability to regulate mTORC1 and the metabolic fate of leucine

  Kim, K., Yoo, H. C., Kim, B. G., Kim, S., Sung, Y., Yoon, I., Yu, Y. C., Park, S. J., Kim, J. H., Myung, K., Hwang, K. Y., Kim, S. & Han, J. M., 2022 Dec, In: Nature communications. 13, 1, 2904.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Leucine 100%
  • Glucose 66%
  • Aptitude 22%
  • Transfer RNA 22%
  • Kinase 11%
  5 Citations (Scopus)

• O-GlcNAcylation: An Emerging Protein Modification Regulating the Hippo Pathway

  Kim, E., Kang, J. G., Jho, E. H., Yang, W. H. & Cho, J. W., 2022 Jun 1, In: Cancers. 14, 12, 3013.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Homeostasis 100%
  • Protein Modification 100%
  • Self Concept 100%
  • Cancer Cell 50%
  • Glycosylation 50%
  2 Citations (Scopus)

• Poly-ADP ribosylation of p21 by tankyrases promotes p21 degradation and regulates cell cycle progression

  Jung, M., Kim, W., Cho, J. W., Yang, W. H. & Chung, I. K., 2022 Nov, In: Biochemical Journal. 479, 22, p. 2379-2394 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • P21 100%
  • Degradation 41%
  • Cell Cycle Progression 33%
  • Protein 25%
  • Phosphorylation 16%

• Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling

  Ryu, Y. C., Kim, Y. R., Park, J., Choi, S., Ryu, W. J., Kim, G. U., Kim, E., Hwang, Y., Kim, H., Han, G., Lee, S. H. & Choi, K. Y., 2022 Dec, In: Pharmaceutics. 14, 12, 2774.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pyruvate Kinase 100%
  • Catenin 66%
  • Regeneration 50%
  • Stem Cell 33%
  • Growth 33%
  2 Citations (Scopus)

• Roles of Keratins in Intestine

  Mun, J., Hur, W. & Ku, N. O., 2022 Jul, In: International journal of molecular sciences. 23, 14, 8051.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Keratin 100%
  • Intestine 88%
  • Colon 22%
  • Small Intestine 22%
  • Enteropathy 22%
  1 Citation (Scopus)

• Selective cytotoxicity of a novel mitochondrial complex I inhibitor, YK-135, against EMT-subtype gastric cancer cell lines due to impaired glycolytic capacity

  Sung, Y., Cha, S., Kim, S. B., Kim, H., Choi, S., Oh, S., Kim, M., Lee, Y., Kwon, G., Lee, J., Lee, J. Y., Han, G. & Kim, H. S., 2022, In: BMB reports. 55, 12, p. 645-650 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mesenchymal-Epithelial Transition 100%
  • Cancer Cell 71%
  • Cytotoxicity 42%
  • Homeostasis 14%
  • AMP-activated Protein Kinase 14%

• Short Term Isocaloric Ketogenic Diet Modulates NLRP3 Inflammasome Via B-hydroxybutyrate and Fibroblast Growth Factor 21

  Kim, E. R., Kim, S. R., Cho, W., Lee, S. G., Kim, S. H., Kim, J. H., Choi, E., Kim, J. H., Yu, J. W., Lee, B. W., Kang, E. S., Cha, B. S., Lee, M. S., Cho, J. W., Jeon, J. Y. & Lee, Y. H., 2022 Apr 28, In: Frontiers in Immunology. 13, 843520.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ketogenic Diet 100%
  • FGF21 55%
  • Fibroblast Growth Factor 21 55%
  • Interleukin 1 33%
  • Secretion (Process) 33%
  5 Citations (Scopus)

• Wnt/β-catenin signaling activator restores hair regeneration suppressed by diabetes mellitus

  Ryu, Y. C., Kim, Y. R., Park, J., Choi, S., Kim, G. U., Kim, E., Hwang, Y., Kim, H., Bak, S. S., Lee, J. E., Sung, Y. K., Han, G., Lee, S. H. & Choi, K. Y., 2022, In: BMB reports. 55, 11, p. 559-564 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Diabetes Mellitus 100%
  • Catenin 87%
  • Minoxidil 37%
  • Hair Follicle 37%
  • Hair 37%
  1 Citation (Scopus)

• ZNF204P is a stemness-associated oncogenic long non-coding RNA in hepatocellular carcinoma

  Hwang, J. H., Lee, J., Choi, W. Y., Kim, M. J., Lee, J., Chu, K. H. B., Kim, L. K. & Kim, Y. J., 2022, In: BMB reports. 55, 6, p. 281-286 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Long Untranslated RNA 100%
  • Hepatocellular Carcinoma 66%
  • Drug Resistance 66%
  • Therapeutic Procedure 66%
  • SOX2 66%
  1 Citation (Scopus)
• 2021

  Aminoacyl-tRNA synthetases and amino acid signaling

  Yu, Y. C., Han, J. M. & Kim, S., 2021 Jan, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1868, 1, 118889.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Aminoacyl tRNA Synthetase 100%
  • Amino Acids 100%
  • Protein Biosynthesis 28%
  • Transfer RNA 28%
  • Cell Growth 14%
  23 Citations (Scopus)

• Development of a DABCO-Succinic Acid Based Catalytic System for the Aza-Michael Addition and Aza-Michael/Knoevenagel Tandem Reaction of Thiazolidine-2,4-dione to Electron Deficient Alkenes

  Jung, K., Kim, S., Choi, S., Kim, I. & Han, G., 2021 Dec 3, In: Journal of Organic Chemistry. 86, 23, p. 16785-16794 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Thiazolidine 100%
  • Aza-Michael Addition 100%
  • Alkene 40%
  • Electron Particle 40%
  • Knoevenagel Condensation 40%
  4 Citations (Scopus)

• Early Diagnostic Ability of Human Complement Factor B in Pancreatic Cancer Is Partly Linked to Its Potential Tumor-Promoting Role

  Lee, M. J., Na, K., Shin, H., Kim, C. Y., Cho, J. Y., Kang, C. M., Kim, S. H., Kim, H., Choi, H. J., Lee, C. K., Bae, S., Son, S. & Paik, Y. K., 2021 Dec 3, In: Journal of Proteome Research. 20, 12, p. 5315-5328 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Pancreas Cancer 100%
  • Comb 55%
  • Diagnosis 44%
  • CA19-9 33%
  • Patient 33%
  2 Citations (Scopus)

• Keratin 8/18 regulate the akt signaling pathway

  Lim, Y., Kim, S., Yoon, H. N. & Ku, N. O., 2021 Sept 1, In: International journal of molecular sciences. 22, 17, 9227.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Signal Transduction 100%
  • Keratin 8 100%
  • Cytokeratin 8 100%
  • Cell Signaling 100%
  • Keratin 18 87%
  3 Citations (Scopus)

• Keratin 8 mutations in transgenic mice predispose to lung injury

  Kim, S., Lim, Y., Lee, S. Y., Yoon, H. N., Yi, H., Jang, K. H. & Ku, N. O., 2021 Aug, In: Journal of cell science. 134, 15, jcs250167.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Keratin 8 100%
  • Lung Injury 77%
  • Transgenic Mouse 66%
  • Mouse 66%
  • Mutant 33%
  1 Citation (Scopus)

• Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation

  Kim, S., Yoon, I., Son, J., Park, J., Kim, K., Lee, J. H., Park, S. Y., Kang, B. S., Han, J. M., Hwang, K. Y. & Kim, S., 2021 Apr 27, In: Cell Reports. 35, 4, 109031.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Leucine 100%
  • Mammalian Target of Rapamycin Complex 1 40%
  • Conformational Change 20%
  • Transfer RNA 20%
  • Crystal Structure 10%
  13 Citations (Scopus)

• Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

  Cho, A. N., Jin, Y., An, Y., Kim, J., Choi, Y. S., Lee, J. S., Kim, J., Choi, W. Y., Koo, D. J., Yu, W., Chang, G. E., Kim, D. Y., Jo, S. H., Kim, J., Kim, S. Y., Kim, Y. G., Kim, J. Y., Choi, N., Cheong, E., Kim, Y. J., & 3 othersJe, H. S., Kang, H. C. & Cho, S. W., 2021 Dec 1, In: Nature communications. 12, 1, 4730.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Brain 100%
  • Organoid 37%
  • Culture 20%
  • Extracellular Matrix 12%
  • Development 12%
  98 Citations (Scopus)

• Neu3 neuraminidase induction triggers intestinal inflammation and colitis in a model of recurrent human food-poisoning

  Yang, W. H., Westman, J. S., Heithoff, D. M., Sperandio, M., Cho, J. W., Mahan, M. J. & Marth, J. D., 2021 Jul 20, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 29, e2100937118.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sialidase 100%
  • Colitis 100%
  • Neuraminidase 100%
  • Enteritis 60%
  • Inflammation 60%
  15 Citations (Scopus)

• Novel positive allosteric modulator of protease-activated receptor 1 promotes skin wound healing in hairless mice

  Seo, Y., Heo, Y., Jo, S., Park, S. H., Lee, C., Chang, J., Jeon, D. K., Kim, T. G., Han, G. & Namkung, W., 2021 Sept, In: British Journal of Pharmacology. 178, 17, p. 3414-3427 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteinase Activated Receptor 1 100%
  • Wound Healing 42%
  • Skin Injury 35%
  • Positive Allosteric Modulator 21%
  • Hairless Mouse 14%
  3 Citations (Scopus)

• O-GlcNAcylated p53 in the liver modulates hepatic glucose production

  Gonzalez-Rellan, M. J., Fondevila, M. F., Fernandez, U., Rodríguez, A., Varela-Rey, M., Veyrat-Durebex, C., Seoane, S., Bernardo, G., Lopitz-Otsoa, F., Fernández-Ramos, D., Bilbao, J., Iglesias, C., Novoa, E., Ameneiro, C., Senra, A., Beiroa, D., Cuñarro, J., DP Chantada-Vazquez, M., Garcia-Vence, M., Bravo, S. B., & 23 othersDa Silva Lima, N., Porteiro, B., Carneiro, C., Vidal, A., Tovar, S., Müller, T. D., Ferno, J., Guallar, D., Fidalgo, M., Sabio, G., Herzig, S., Yang, W. H., Cho, J. W., Martinez-Chantar, M. L., Perez-Fernandez, R., López, M., Dieguez, C., Mato, J. M., Millet, O., Coppari, R., Woodhoo, A., Fruhbeck, G. & Nogueiras, R., 2021 Dec 1, In: Nature communications. 12, 1, 5068.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • P53 100%
  • Glucose 15%
  • Glucose Homeostasis 15%
  • Gluconeogenesis 15%
  • Mouse 15%
  26 Citations (Scopus)

• O-Linked N-Acetylglucosamine Modification of Mitochondrial Antiviral Signaling Protein Regulates Antiviral Signaling by Modulating Its Activity

  Seo, J., Park, Y. S., Kweon, T. H., Kang, J., Son, S., Kim, H. B., Seo, Y. R., Kang, M. J., Yi, E. C., Lee, Y. H., Kim, J. H., Park, B., Yang, W. H. & Cho, J. W., 2021 Feb 2, In: Frontiers in Immunology. 11, 589259.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mitochondrial Antiviral-Signaling Protein 100%
  • Serine 33%
  • RNA Virus 16%
  • Signal Transduction 16%
  • Posttranslational Modification 16%
  2 Citations (Scopus)

• Profiling of conditionally reprogrammed cell lines for in vitro chemotherapy response prediction of pancreatic cancer

  Lee, H. S., Kim, E., Lee, J., Park, S. J., Hwang, H. K., Park, C. H., Jo, S. Y., Kang, C. M., Hong, S. M., Kang, H., Jo, J. H., Cho, I. R., Chung, M. J., Park, J. Y., Park, S. W., Song, S. Y., Han, J. M., Kim, S. & Bang, S., 2021 Mar, In: EBioMedicine. 65, 103218.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mutation 100%
  • Patient 83%
  • Cells 66%
  • Anticarcinogen 50%
  • In Vitro 33%
  5 Citations (Scopus)

• Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project

  Omenn, G. S., Lane, L., Overall, C. M., Paik, Y. K., Cristea, I. M., Corrales, F. J., Lindskog, C., Weintraub, S., Roehrl, M. H. A., Liu, S., Bandeira, N., Srivastava, S., Chen, Y. J., Aebersold, R., Moritz, R. L. & Deutsch, E. W., 2021 Dec 3, In: Journal of Proteome Research. 20, 12, p. 5227-5240 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Proteome 100%
  • Protein 50%
  • Proteomics 33%
  • Antibodies 16%
  • Mass Spectrometry 16%
  25 Citations (Scopus)

• Randomized, Controlled Trial to Evaluate the Effect of Dapagliflozin on Left Ventricular Diastolic Function in Patients With Type 2 Diabetes Mellitus: The IDDIA Trial

  Shim, C. Y., Seo, J., Cho, I., Lee, C. J., Cho, I. J., Lhagvasuren, P., Kang, S. M., Ha, J. W., Han, G., Jang, Y. & Hong, G. R., 2021 Feb 2, In: Circulation. 143, 5, p. 510-512 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  40 Citations (Scopus)

• Revealing the roles of keratin 8/18-associated signaling proteins involved in the development of hepatocellular carcinoma

  Lim, Y. & Ku, N. O., 2021 Jun 2, In: International journal of molecular sciences. 22, 12, 6401.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Keratin 8 100%
  • Cytokeratin 8 100%
  • Keratin 18 85%
  • Cytokeratin 18 85%
  • Hepatocellular Carcinoma 71%
  2 Citations (Scopus)

• Structure-based modification of pyrazolone derivatives to inhibit mTORC1 by targeting the leucyl-tRNA synthetase-RagD interaction

  Kim, J. H., Jung, K., Lee, C., Song, D., Kim, K., Yoo, H. C., Park, S. J., Kang, J. S., Lee, K. R., Kim, S., Han, J. M. & Han, G., 2021 Jul, In: Bioorganic Chemistry. 112, 104907.

  Research output: Contribution to journal › Article › peer-review

  • Leucine Transfer RNA Ligase 100%
  • Leucine 50%
  • Enzyme 25%
  • Diseases 25%
  • Functional Groups 25%
  3 Citations (Scopus)

• Suppressing pyroptosis augments post‐transplant survival of stem cells and cardiac function following ischemic injury

  Lee, C. Y., Lee, S., Jeong, S., Lee, J., Seo, H. H., Shin, S., Park, J. H., Song, B. W., Kim, I. K., Choi, J. W., Kim, S. W., Han, G., Lim, S. & Hwang, K. C., 2021 Aug 1, In: International journal of molecular sciences. 22, 15, 7946.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Stem Cell 100%
  • Pyroptosis 85%
  • Heart 71%
  • Programmed Cell Death 57%
  • Death 42%
  1 Citation (Scopus)

• Suppression of Wnt/β-catenin and RAS/ERK pathways provides a therapeutic strategy for gemcitabine-resistant pancreatic cancer

  Ryu, W. J., Han, G., Lee, S. H. & Choi, K. Y., 2021 Apr 16, In: Biochemical and Biophysical Research Communications. 549, p. 40-46 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pancreas Cancer 100%
  • Gemcitabine 88%
  • Catenin 66%
  • Patient 33%
  • Therapeutic Procedure 33%
  13 Citations (Scopus)
• 2020

  A high-stringency blueprint of the human proteome

  Adhikari, S., Nice, E. C., Deutsch, E. W., Lane, L., Omenn, G. S., Pennington, S. R., Paik, Y. K., Overall, C. M., Corrales, F. J., Cristea, I. M., Van Eyk, J. E., Uhlén, M., Lindskog, C., Chan, D. W., Bairoch, A., Waddington, J. C., Justice, J. L., LaBaer, J., Rodriguez, H., He, F., & 26 othersKostrzewa, M., Ping, P., Gundry, R. L., Stewart, P., Srivastava, S., Srivastava, S., Nogueira, F. C. S., Domont, G. B., Vandenbrouck, Y., Lam, M. P. Y., Wennersten, S., Vizcaino, J. A., Wilkins, M., Schwenk, J. M., Lundberg, E., Bandeira, N., Marko-Varga, G., Weintraub, S. T., Pineau, C., Kusebauch, U., Moritz, R. L., Ahn, S. B., Palmblad, M., Snyder, M. P., Aebersold, R. & Baker, M. S., 2020 Dec 1, In: Nature communications. 11, 1, 5301.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Proteome 100%
  • Electric Potential 12%
  • Comprehension 12%
  • Health 12%
  110 Citations (Scopus)

• A molecular basis for reciprocal regulation between pheromones and hormones in response to dietary cues in C. Elegans

  Park, S., Park, J. Y. & Paik, Y. K., 2020 Apr 1, In: International journal of molecular sciences. 21, 7, p. 1-12 12 p., 2366.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Pheromone 100%
  • Insulin 44%
  • Regulatory Mechanism 33%
  • Aging 22%
  • Nested Gene 22%
  1 Citation (Scopus)

• A novel functional cross-interaction between opioid and pheromone signaling may be involved in stress avoidance in Caenorhabditis elegans

  Park, J. Y., Cheong, M. C., Cho, J. Y., Koo, H. S. & Paik, Y. K., 2020 Dec 1, In: Scientific reports. 10, 1, 7524.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Opioid 100%
  • Pheromone 75%
  • Stress 62%
  • Mutant 37%
  • Caenorhabditis Elegans 25%
  3 Citations (Scopus)

• A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells

  Yoo, H. C., Park, S. J., Nam, M., Kang, J., Kim, K., Yeo, J. H., Kim, J. K., Heo, Y., Lee, H. S., Lee, M. Y., Lee, C. W., Kang, J. S., Kim, Y. H., Lee, J., Choi, J., Hwang, G. S., Bang, S. & Han, J. M., 2020 Feb 4, In: Cell Metabolism. 31, 2, p. 267-283.e12

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • SLC1A5 100%
  • Glutamine 100%
  • Cancer Cell 55%
  • Reprogramming 33%
  • Homeostasis 11%
  170 Citations (Scopus)